Membrane fusion in muscle development and repair

Mature skeletal muscle forms from the fusion of skeletal muscle precursor cells, myoblasts. Myoblasts fuse to other myoblasts to generate multinucleate myotubes during myogenesis, and myoblasts also fuse to other myotubes during muscle growth and repair. Proteins within myoblasts and myotubes regula...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Seminars in cell & developmental biology 2015-09, Vol.45, p.48-56
Hauptverfasser:	Demonbreun, Alexis R., Biersmith, Bridget H., McNally, Elizabeth M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell Adhesion Cell Membrane - physiology Development Fusion Humans Intracellular Signaling Peptides and Proteins - physiology Membrane Membrane Fusion Muscle Muscle Development Muscle, Skeletal - physiology Myoblast Myoblasts - physiology Repair Wound Healing
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

container_end_page	56
container_issue
container_start_page	48
container_title	Seminars in cell & developmental biology
container_volume	45
creator	Demonbreun, Alexis R. Biersmith, Bridget H. McNally, Elizabeth M.
description	Mature skeletal muscle forms from the fusion of skeletal muscle precursor cells, myoblasts. Myoblasts fuse to other myoblasts to generate multinucleate myotubes during myogenesis, and myoblasts also fuse to other myotubes during muscle growth and repair. Proteins within myoblasts and myotubes regulate complex processes such as elongation, migration, cell adherence, cytoskeletal reorganization, membrane coalescence, and ultimately fusion. Recent studies have identified cell surface proteins, intracellular proteins, and extracellular signaling molecules required for the proper fusion of muscle. Many proteins that actively participate in myoblast fusion also coordinate membrane repair. Here we will review mammalian membrane fusion with specific attention to proteins that mediate myoblast fusion and muscle repair.
doi_str_mv	10.1016/j.semcdb.2015.10.026
format	Article
fullrecord	<record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4679555</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S1084952115002232</els_id><sourcerecordid>1749609976</sourcerecordid><originalsourceid>FETCH-LOGICAL-c514t-b0a7481de236befd78d5cc8b6b440db517941f46ce6dc4747f2406d0584a74ed3</originalsourceid><addsrcrecordid>eNp9kE1PwzAMhiMEYmPwDxDqkUtL0jpJe0FCE1_SEBc4R23iQqZ-kayT-Pdk2hhw4WTL9vvafgg5ZzRhlImrZeKx1aZKUsp4KCU0FQdkymgh4kxkcLjJc4gLnrIJOfF-SSmFIhXHZJIKnknI6JTQJ2wrV3YY1aO3fRfZLmpHrxuMDK6x6YcWu1VUdiZyOJTWnZKjumw8nu3ijLze3b7MH-LF8_3j_GYRa85gFVe0lJAzg2kmKqyNzA3XOq9EBUBNxZksgNUgNAqjQYKsU6DCUJ5DEKLJZuR66zuMVYtGhytc2ajB2bZ0n6ovrfrb6ey7euvXCoQsOOfB4HJn4PqPEf1KtdZrbJrwbD96xSQUghaFFGEUtqPa9d47rPdrGFUb2GqptrDVBvamGmAH2cXvE_eib7o_P2AAtbbolNcWO43GOtQrZXr7_4Yv3YCSqg</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1749609976</pqid></control><display><type>article</type><title>Membrane fusion in muscle development and repair</title><source>MEDLINE</source><source>Elsevier ScienceDirect Journals</source><creator>Demonbreun, Alexis R. ; Biersmith, Bridget H. ; McNally, Elizabeth M.</creator><creatorcontrib>Demonbreun, Alexis R. ; Biersmith, Bridget H. ; McNally, Elizabeth M.</creatorcontrib><description>Mature skeletal muscle forms from the fusion of skeletal muscle precursor cells, myoblasts. Myoblasts fuse to other myoblasts to generate multinucleate myotubes during myogenesis, and myoblasts also fuse to other myotubes during muscle growth and repair. Proteins within myoblasts and myotubes regulate complex processes such as elongation, migration, cell adherence, cytoskeletal reorganization, membrane coalescence, and ultimately fusion. Recent studies have identified cell surface proteins, intracellular proteins, and extracellular signaling molecules required for the proper fusion of muscle. Many proteins that actively participate in myoblast fusion also coordinate membrane repair. Here we will review mammalian membrane fusion with specific attention to proteins that mediate myoblast fusion and muscle repair.</description><identifier>ISSN: 1084-9521</identifier><identifier>EISSN: 1096-3634</identifier><identifier>DOI: 10.1016/j.semcdb.2015.10.026</identifier><identifier>PMID: 26537430</identifier><language>eng</language><publisher>England: Elsevier Ltd</publisher><subject>Animals ; Cell Adhesion ; Cell Membrane - physiology ; Development ; Fusion ; Humans ; Intracellular Signaling Peptides and Proteins - physiology ; Membrane ; Membrane Fusion ; Muscle ; Muscle Development ; Muscle, Skeletal - physiology ; Myoblast ; Myoblasts - physiology ; Repair ; Wound Healing</subject><ispartof>Seminars in cell & developmental biology, 2015-09, Vol.45, p.48-56</ispartof><rights>2015 Elsevier Ltd</rights><rights>Copyright © 2015 Elsevier Ltd. All rights reserved.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c514t-b0a7481de236befd78d5cc8b6b440db517941f46ce6dc4747f2406d0584a74ed3</citedby><cites>FETCH-LOGICAL-c514t-b0a7481de236befd78d5cc8b6b440db517941f46ce6dc4747f2406d0584a74ed3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.semcdb.2015.10.026$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>230,314,777,781,882,3537,27905,27906,45976</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/26537430$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Demonbreun, Alexis R.</creatorcontrib><creatorcontrib>Biersmith, Bridget H.</creatorcontrib><creatorcontrib>McNally, Elizabeth M.</creatorcontrib><title>Membrane fusion in muscle development and repair</title><title>Seminars in cell & developmental biology</title><addtitle>Semin Cell Dev Biol</addtitle><description>Mature skeletal muscle forms from the fusion of skeletal muscle precursor cells, myoblasts. Myoblasts fuse to other myoblasts to generate multinucleate myotubes during myogenesis, and myoblasts also fuse to other myotubes during muscle growth and repair. Proteins within myoblasts and myotubes regulate complex processes such as elongation, migration, cell adherence, cytoskeletal reorganization, membrane coalescence, and ultimately fusion. Recent studies have identified cell surface proteins, intracellular proteins, and extracellular signaling molecules required for the proper fusion of muscle. Many proteins that actively participate in myoblast fusion also coordinate membrane repair. Here we will review mammalian membrane fusion with specific attention to proteins that mediate myoblast fusion and muscle repair.</description><subject>Animals</subject><subject>Cell Adhesion</subject><subject>Cell Membrane - physiology</subject><subject>Development</subject><subject>Fusion</subject><subject>Humans</subject><subject>Intracellular Signaling Peptides and Proteins - physiology</subject><subject>Membrane</subject><subject>Membrane Fusion</subject><subject>Muscle</subject><subject>Muscle Development</subject><subject>Muscle, Skeletal - physiology</subject><subject>Myoblast</subject><subject>Myoblasts - physiology</subject><subject>Repair</subject><subject>Wound Healing</subject><issn>1084-9521</issn><issn>1096-3634</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2015</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kE1PwzAMhiMEYmPwDxDqkUtL0jpJe0FCE1_SEBc4R23iQqZ-kayT-Pdk2hhw4WTL9vvafgg5ZzRhlImrZeKx1aZKUsp4KCU0FQdkymgh4kxkcLjJc4gLnrIJOfF-SSmFIhXHZJIKnknI6JTQJ2wrV3YY1aO3fRfZLmpHrxuMDK6x6YcWu1VUdiZyOJTWnZKjumw8nu3ijLze3b7MH-LF8_3j_GYRa85gFVe0lJAzg2kmKqyNzA3XOq9EBUBNxZksgNUgNAqjQYKsU6DCUJ5DEKLJZuR66zuMVYtGhytc2ajB2bZ0n6ovrfrb6ey7euvXCoQsOOfB4HJn4PqPEf1KtdZrbJrwbD96xSQUghaFFGEUtqPa9d47rPdrGFUb2GqptrDVBvamGmAH2cXvE_eib7o_P2AAtbbolNcWO43GOtQrZXr7_4Yv3YCSqg</recordid><startdate>201509</startdate><enddate>201509</enddate><creator>Demonbreun, Alexis R.</creator><creator>Biersmith, Bridget H.</creator><creator>McNally, Elizabeth M.</creator><general>Elsevier Ltd</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>201509</creationdate><title>Membrane fusion in muscle development and repair</title><author>Demonbreun, Alexis R. ; Biersmith, Bridget H. ; McNally, Elizabeth M.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c514t-b0a7481de236befd78d5cc8b6b440db517941f46ce6dc4747f2406d0584a74ed3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2015</creationdate><topic>Animals</topic><topic>Cell Adhesion</topic><topic>Cell Membrane - physiology</topic><topic>Development</topic><topic>Fusion</topic><topic>Humans</topic><topic>Intracellular Signaling Peptides and Proteins - physiology</topic><topic>Membrane</topic><topic>Membrane Fusion</topic><topic>Muscle</topic><topic>Muscle Development</topic><topic>Muscle, Skeletal - physiology</topic><topic>Myoblast</topic><topic>Myoblasts - physiology</topic><topic>Repair</topic><topic>Wound Healing</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Demonbreun, Alexis R.</creatorcontrib><creatorcontrib>Biersmith, Bridget H.</creatorcontrib><creatorcontrib>McNally, Elizabeth M.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Seminars in cell & developmental biology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Demonbreun, Alexis R.</au><au>Biersmith, Bridget H.</au><au>McNally, Elizabeth M.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Membrane fusion in muscle development and repair</atitle><jtitle>Seminars in cell & developmental biology</jtitle><addtitle>Semin Cell Dev Biol</addtitle><date>2015-09</date><risdate>2015</risdate><volume>45</volume><spage>48</spage><epage>56</epage><pages>48-56</pages><issn>1084-9521</issn><eissn>1096-3634</eissn><abstract>Mature skeletal muscle forms from the fusion of skeletal muscle precursor cells, myoblasts. Myoblasts fuse to other myoblasts to generate multinucleate myotubes during myogenesis, and myoblasts also fuse to other myotubes during muscle growth and repair. Proteins within myoblasts and myotubes regulate complex processes such as elongation, migration, cell adherence, cytoskeletal reorganization, membrane coalescence, and ultimately fusion. Recent studies have identified cell surface proteins, intracellular proteins, and extracellular signaling molecules required for the proper fusion of muscle. Many proteins that actively participate in myoblast fusion also coordinate membrane repair. Here we will review mammalian membrane fusion with specific attention to proteins that mediate myoblast fusion and muscle repair.</abstract><cop>England</cop><pub>Elsevier Ltd</pub><pmid>26537430</pmid><doi>10.1016/j.semcdb.2015.10.026</doi><tpages>9</tpages><oa>free_for_read</oa></addata></record>
fulltext	fulltext
identifier	ISSN: 1084-9521
ispartof	Seminars in cell & developmental biology, 2015-09, Vol.45, p.48-56
issn	1084-9521 1096-3634
language	eng
recordid	cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4679555
source	MEDLINE; Elsevier ScienceDirect Journals
subjects	Animals Cell Adhesion Cell Membrane - physiology Development Fusion Humans Intracellular Signaling Peptides and Proteins - physiology Membrane Membrane Fusion Muscle Muscle Development Muscle, Skeletal - physiology Myoblast Myoblasts - physiology Repair Wound Healing
title	Membrane fusion in muscle development and repair
url	https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-20T17%3A08%3A33IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Membrane%20fusion%20in%20muscle%20development%20and%20repair&rft.jtitle=Seminars%20in%20cell%20&%20developmental%20biology&rft.au=Demonbreun,%20Alexis%20R.&rft.date=2015-09&rft.volume=45&rft.spage=48&rft.epage=56&rft.pages=48-56&rft.issn=1084-9521&rft.eissn=1096-3634&rft_id=info:doi/10.1016/j.semcdb.2015.10.026&rft_dat=%3Cproquest_pubme%3E1749609976%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1749609976&rft_id=info:pmid/26537430&rft_els_id=S1084952115002232&rfr_iscdi=true