Analysis of histone modifications at human ribosomal DNA in liver cancer cell

Human liver cancer is the cancer commonly seen clinically. The transcription of ribosomal DNA (rDNA) is a critical step for cells and epigenetic marks such as post-translational histone modifications have been involved in the regulation of rDNA transcription. But less is known about the pathogenesis...

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Veröffentlicht in:	Scientific reports 2015-12, Vol.5 (1), p.18100-18100, Article 18100
Hauptverfasser:	Yu, Feng, Shen, Xingyong, Fan, Li, Yu, Zhaocai
Format:	Artikel
Sprache:	eng
Schlagworte:	631/337/176 631/67 631/80/458 692/699/67 Blotting, Western CCCTC-Binding Factor Chromatin Chromatin Immunoprecipitation Deoxyribonucleic acid DNA DNA, Ribosomal - genetics DNA, Ribosomal - metabolism Gene Expression Regulation, Neoplastic Gene regulation Genomes Hep G2 Cells Hepatocytes Histone Code Histones - genetics Histones - metabolism Humanities and Social Sciences Humans Liver cancer Liver Neoplasms - genetics Liver Neoplasms - metabolism Liver Neoplasms - pathology Lysine - metabolism Methylation multidisciplinary Pol1 Transcription Initiation Complex Proteins - genetics Pol1 Transcription Initiation Complex Proteins - metabolism Post-translation Promoter Regions, Genetic - genetics Protein Processing, Post-Translational Repressor Proteins - genetics Repressor Proteins - metabolism Reverse Transcriptase Polymerase Chain Reaction Ribosomal DNA RNA Interference Science Spacer Transcription
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