Problems associated with reconstitution, administration, and storage of antibiotic suspensions for pediatrics: a cross-sectional study in Nablus city, Palestine
The objective of this study was to evaluate the appropriateness of antibiotic suspensions use for pediatrics among Palestinian mothers' including their reconstitution, dose administration, duration, and storage conditions. This study was a questionnaire based cross sectional descriptive study....
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| creator | Al-Ramahi, Rowa' J Zaid, Abd Al Naser Anabousi, Haya |
| description | The objective of this study was to evaluate the appropriateness of antibiotic suspensions use for pediatrics among Palestinian mothers' including their reconstitution, dose administration, duration, and storage conditions.
This study was a questionnaire based cross sectional descriptive study. It was conducted at a governmental primary healthcare center and a pediatric private clinic in Nablus city between January and March 2013. A sample of 400 mothers were met and asked to answer a face to face questionnaire.
The results showed that 347 (86.8 %) of mothers told that they read instructions, 311 (77.8 %) could understand manufacturers' instructions, and 176 (44.0 %) of mothers asked pharmacists for advice when instructions were not well understood. In order to prepare antibiotic suspension, 302 (75.5 %) used boiled then cooled water, 192 (48.4 %) of mothers used a syringe to measure the needed amount of water, and 304 (76.6 %) added water in two steps, 392 (98.0 %) of mothers claimed that they shook the suspension bottle before use. Regarding dose administration, 313 (78.2 %) considered syringe as the most accurate tool for dose administration, most of mothers told that they gave drug dose with major meals when direction were to give three times daily, about use duration only 6 (1.5 %) mothers said that they used antibiotic suspension after 2 weeks, and 53 (6.5 %) gave left over antibiotic suspension to another child. One hundred seventy seven (44.2 %) mothers told they stored dry powder antibiotic in medicinal cabinet, while 226 (56.5 %) of them stored suspension in refrigerator.
The results reflect a good level of correct practice. However, there is a room for improvement. The pharmacists are recommended to explain the correct directions, to supply a syringe with suitable calibration for dose administration, and to counsel parents about suitable storage condition, frequency of dosing and duration of use. |
| doi_str_mv | 10.1186/s13104-015-1746-z |
| format | Article |
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This study was a questionnaire based cross sectional descriptive study. It was conducted at a governmental primary healthcare center and a pediatric private clinic in Nablus city between January and March 2013. A sample of 400 mothers were met and asked to answer a face to face questionnaire.
The results showed that 347 (86.8 %) of mothers told that they read instructions, 311 (77.8 %) could understand manufacturers' instructions, and 176 (44.0 %) of mothers asked pharmacists for advice when instructions were not well understood. In order to prepare antibiotic suspension, 302 (75.5 %) used boiled then cooled water, 192 (48.4 %) of mothers used a syringe to measure the needed amount of water, and 304 (76.6 %) added water in two steps, 392 (98.0 %) of mothers claimed that they shook the suspension bottle before use. Regarding dose administration, 313 (78.2 %) considered syringe as the most accurate tool for dose administration, most of mothers told that they gave drug dose with major meals when direction were to give three times daily, about use duration only 6 (1.5 %) mothers said that they used antibiotic suspension after 2 weeks, and 53 (6.5 %) gave left over antibiotic suspension to another child. One hundred seventy seven (44.2 %) mothers told they stored dry powder antibiotic in medicinal cabinet, while 226 (56.5 %) of them stored suspension in refrigerator.
The results reflect a good level of correct practice. However, there is a room for improvement. The pharmacists are recommended to explain the correct directions, to supply a syringe with suitable calibration for dose administration, and to counsel parents about suitable storage condition, frequency of dosing and duration of use.</description><identifier>ISSN: 1756-0500</identifier><identifier>EISSN: 1756-0500</identifier><identifier>DOI: 10.1186/s13104-015-1746-z</identifier><identifier>PMID: 26652747</identifier><language>eng</language><publisher>England: BioMed Central Ltd</publisher><subject>Adolescent ; Adult ; Anti-Bacterial Agents - administration & dosage ; Anti-Bacterial Agents - chemistry ; Antibiotics ; Chi-Square Distribution ; Child, Preschool ; Cross-Sectional Studies ; Drug Compounding - methods ; Drug Storage - methods ; Female ; Humans ; Infant ; Middle Aged ; Middle East ; Mothers - education ; Patient Education as Topic - methods ; Pediatrics ; Pediatrics - methods ; Pharmacists ; Primary health care ; Primary Health Care - methods ; Socioeconomic Factors ; Surveys and Questionnaires ; Suspensions ; Young Adult</subject><ispartof>BMC research notes, 2015-12, Vol.8 (1), p.760-760, Article 760</ispartof><rights>COPYRIGHT 2015 BioMed Central Ltd.</rights><rights>Copyright BioMed Central 2015</rights><rights>Al-Ramahi et al. 2015</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c443z-ed01d730b08afe82c35494d6c296682fa568770f76186b8f100f7c9042e069213</citedby><cites>FETCH-LOGICAL-c443z-ed01d730b08afe82c35494d6c296682fa568770f76186b8f100f7c9042e069213</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673755/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673755/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,315,728,781,785,865,886,27926,27927,53793,53795</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/26652747$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Al-Ramahi, Rowa' J</creatorcontrib><creatorcontrib>Zaid, Abd Al Naser</creatorcontrib><creatorcontrib>Anabousi, Haya</creatorcontrib><title>Problems associated with reconstitution, administration, and storage of antibiotic suspensions for pediatrics: a cross-sectional study in Nablus city, Palestine</title><title>BMC research notes</title><addtitle>BMC Res Notes</addtitle><description>The objective of this study was to evaluate the appropriateness of antibiotic suspensions use for pediatrics among Palestinian mothers' including their reconstitution, dose administration, duration, and storage conditions.
This study was a questionnaire based cross sectional descriptive study. It was conducted at a governmental primary healthcare center and a pediatric private clinic in Nablus city between January and March 2013. A sample of 400 mothers were met and asked to answer a face to face questionnaire.
The results showed that 347 (86.8 %) of mothers told that they read instructions, 311 (77.8 %) could understand manufacturers' instructions, and 176 (44.0 %) of mothers asked pharmacists for advice when instructions were not well understood. In order to prepare antibiotic suspension, 302 (75.5 %) used boiled then cooled water, 192 (48.4 %) of mothers used a syringe to measure the needed amount of water, and 304 (76.6 %) added water in two steps, 392 (98.0 %) of mothers claimed that they shook the suspension bottle before use. Regarding dose administration, 313 (78.2 %) considered syringe as the most accurate tool for dose administration, most of mothers told that they gave drug dose with major meals when direction were to give three times daily, about use duration only 6 (1.5 %) mothers said that they used antibiotic suspension after 2 weeks, and 53 (6.5 %) gave left over antibiotic suspension to another child. One hundred seventy seven (44.2 %) mothers told they stored dry powder antibiotic in medicinal cabinet, while 226 (56.5 %) of them stored suspension in refrigerator.
The results reflect a good level of correct practice. However, there is a room for improvement. The pharmacists are recommended to explain the correct directions, to supply a syringe with suitable calibration for dose administration, and to counsel parents about suitable storage condition, frequency of dosing and duration of use.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Anti-Bacterial Agents - administration & dosage</subject><subject>Anti-Bacterial Agents - chemistry</subject><subject>Antibiotics</subject><subject>Chi-Square Distribution</subject><subject>Child, Preschool</subject><subject>Cross-Sectional Studies</subject><subject>Drug Compounding - methods</subject><subject>Drug Storage - methods</subject><subject>Female</subject><subject>Humans</subject><subject>Infant</subject><subject>Middle Aged</subject><subject>Middle East</subject><subject>Mothers - education</subject><subject>Patient Education as Topic - methods</subject><subject>Pediatrics</subject><subject>Pediatrics - methods</subject><subject>Pharmacists</subject><subject>Primary health care</subject><subject>Primary Health Care - methods</subject><subject>Socioeconomic Factors</subject><subject>Surveys and Questionnaires</subject><subject>Suspensions</subject><subject>Young Adult</subject><issn>1756-0500</issn><issn>1756-0500</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2015</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><recordid>eNptkl1vFCEUhidGY2v1B3hjSLzRpFNhPoDxwqRp_GjS2F6ot4RhYEszAyuHUXd_jT_Vs-5au8ZwAQee8wLvOUXxlNETxiR_BaxmtCkpa0smGl6u7xWHTLS8pC2l9--sD4pHADeUciYle1gcVJy3lWjEYfHzKsV-tBMQDRCN19kO5LvP1yRZEwNkn-fsYzgmeph88JCT3sVhIJBj0gtLosMw-97H7A2BGZY2AFJAXExkaQfUTd7Aa6KJSRGgBGs2MnpEjXlYER_IR92PMxDj8-qYXOnR4uXBPi4eOD2CfbKbj4rP795-OvtQXly-Pz87vShN09Tr0g6UDaKmPZXaWVmZum26ZuCm6jiXldMtl0JQJ9AC3kvHKK5NR5vKUt5VrD4q3mx1l3M_2cHYgD8d1TL5SaeVitqr_ZPgr9UiflMNF7VoWxR4sRNI8euMj1eTB2PHUQcbZ1BYoa7rKiwAos__QW_inNCMDSU6TqXg8i-1QC-UDy7ivWYjqk4bLjvOaE2ROvkPhWOwk8cKWudxfy_h5V4CMtn-yAs9A6jzyy_7LNuyv4uWrLv1g1G1aUG1bUGFLbj5IFdrzHl218jbjD89V_8CVVzY1Q</recordid><startdate>20151209</startdate><enddate>20151209</enddate><creator>Al-Ramahi, Rowa' J</creator><creator>Zaid, Abd Al Naser</creator><creator>Anabousi, Haya</creator><general>BioMed Central Ltd</general><general>BioMed Central</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>IOV</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>LK8</scope><scope>M0S</scope><scope>M1P</scope><scope>M7P</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20151209</creationdate><title>Problems associated with reconstitution, administration, and storage of antibiotic suspensions for pediatrics: a cross-sectional study in Nablus city, Palestine</title><author>Al-Ramahi, Rowa' J ; Zaid, Abd Al Naser ; Anabousi, Haya</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c443z-ed01d730b08afe82c35494d6c296682fa568770f76186b8f100f7c9042e069213</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2015</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Anti-Bacterial Agents - administration & dosage</topic><topic>Anti-Bacterial Agents - chemistry</topic><topic>Antibiotics</topic><topic>Chi-Square Distribution</topic><topic>Child, Preschool</topic><topic>Cross-Sectional Studies</topic><topic>Drug Compounding - methods</topic><topic>Drug Storage - methods</topic><topic>Female</topic><topic>Humans</topic><topic>Infant</topic><topic>Middle Aged</topic><topic>Middle East</topic><topic>Mothers - education</topic><topic>Patient Education as Topic - methods</topic><topic>Pediatrics</topic><topic>Pediatrics - methods</topic><topic>Pharmacists</topic><topic>Primary health care</topic><topic>Primary Health Care - methods</topic><topic>Socioeconomic Factors</topic><topic>Surveys and Questionnaires</topic><topic>Suspensions</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Al-Ramahi, Rowa' J</creatorcontrib><creatorcontrib>Zaid, Abd Al Naser</creatorcontrib><creatorcontrib>Anabousi, Haya</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Gale In Context: Opposing Viewpoints</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>ProQuest Biological Science Collection</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Biological Science Database</collection><collection>Access via ProQuest (Open Access)</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>BMC research notes</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Al-Ramahi, Rowa' J</au><au>Zaid, Abd Al Naser</au><au>Anabousi, Haya</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Problems associated with reconstitution, administration, and storage of antibiotic suspensions for pediatrics: a cross-sectional study in Nablus city, Palestine</atitle><jtitle>BMC research notes</jtitle><addtitle>BMC Res Notes</addtitle><date>2015-12-09</date><risdate>2015</risdate><volume>8</volume><issue>1</issue><spage>760</spage><epage>760</epage><pages>760-760</pages><artnum>760</artnum><issn>1756-0500</issn><eissn>1756-0500</eissn><abstract>The objective of this study was to evaluate the appropriateness of antibiotic suspensions use for pediatrics among Palestinian mothers' including their reconstitution, dose administration, duration, and storage conditions.
This study was a questionnaire based cross sectional descriptive study. It was conducted at a governmental primary healthcare center and a pediatric private clinic in Nablus city between January and March 2013. A sample of 400 mothers were met and asked to answer a face to face questionnaire.
The results showed that 347 (86.8 %) of mothers told that they read instructions, 311 (77.8 %) could understand manufacturers' instructions, and 176 (44.0 %) of mothers asked pharmacists for advice when instructions were not well understood. In order to prepare antibiotic suspension, 302 (75.5 %) used boiled then cooled water, 192 (48.4 %) of mothers used a syringe to measure the needed amount of water, and 304 (76.6 %) added water in two steps, 392 (98.0 %) of mothers claimed that they shook the suspension bottle before use. Regarding dose administration, 313 (78.2 %) considered syringe as the most accurate tool for dose administration, most of mothers told that they gave drug dose with major meals when direction were to give three times daily, about use duration only 6 (1.5 %) mothers said that they used antibiotic suspension after 2 weeks, and 53 (6.5 %) gave left over antibiotic suspension to another child. One hundred seventy seven (44.2 %) mothers told they stored dry powder antibiotic in medicinal cabinet, while 226 (56.5 %) of them stored suspension in refrigerator.
The results reflect a good level of correct practice. However, there is a room for improvement. The pharmacists are recommended to explain the correct directions, to supply a syringe with suitable calibration for dose administration, and to counsel parents about suitable storage condition, frequency of dosing and duration of use.</abstract><cop>England</cop><pub>BioMed Central Ltd</pub><pmid>26652747</pmid><doi>10.1186/s13104-015-1746-z</doi><tpages>1</tpages><oa>free_for_read</oa></addata></record> |
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| subjects | Adolescent Adult Anti-Bacterial Agents - administration & dosage Anti-Bacterial Agents - chemistry Antibiotics Chi-Square Distribution Child, Preschool Cross-Sectional Studies Drug Compounding - methods Drug Storage - methods Female Humans Infant Middle Aged Middle East Mothers - education Patient Education as Topic - methods Pediatrics Pediatrics - methods Pharmacists Primary health care Primary Health Care - methods Socioeconomic Factors Surveys and Questionnaires Suspensions Young Adult |
| title | Problems associated with reconstitution, administration, and storage of antibiotic suspensions for pediatrics: a cross-sectional study in Nablus city, Palestine |
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