Prognostic value of HPV-mRNA in sentinel lymph nodes of cervical cancer patients with pN0-status

Up to 15% of patients with cervical cancer and pN0-status develop recurrent-disease. This may be due to occult metastatic spread of tumor cells. We evaluated the use of human-papillomavirus-(HPV)-mRNA as a molecular marker for disseminated tumor cells to predict the risk of recurrence. For this pros...

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Veröffentlicht in:	Oncotarget 2015-09, Vol.6 (26), p.23015-23025
Hauptverfasser:	Dürst, Matthias, Hoyer, Heike, Altgassen, Christoph, Greinke, Christiane, Häfner, Norman, Fishta, Alba, Gajda, Mieczyslaw, Mahnert, Ute, Hillemanns, Peter, Dimpfl, Thomas, Lenhard, Miriam, Petry, K Ulrich, Runnebaum, Ingo B, Schneider, Achim
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Clinical Research Paper Female Humans Lymph Nodes - pathology Lymph Nodes - virology Middle Aged Papillomaviridae - genetics Papillomaviridae - isolation & purification Prognosis Prospective Studies RNA, Messenger - genetics RNA, Viral - genetics Uterine Cervical Neoplasms - pathology Uterine Cervical Neoplasms - virology Young Adult
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