N-3 polyunsaturated fatty acids modulate B cell activity in pre-clinical models: Implications for the immune response to infections

B cell antigen presentation, cytokine production, and antibody production are targets of pharmacological intervention in inflammatory and infectious diseases. Here we review recent pre-clinical evidence demonstrating that pharmacologically relevant levels of n-3 polyunsaturated fatty acids (PUFA) de...

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Veröffentlicht in:	European journal of pharmacology 2016-08, Vol.785, p.10-17
Hauptverfasser:	Whelan, Jarrett, Gowdy, Kymberly M., Shaikh, Saame Raza
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals B cells B-Lymphocytes - cytology B-Lymphocytes - drug effects B-Lymphocytes - immunology B-Lymphocytes - metabolism Disease Models, Animal Fatty Acids, Omega-3 - pharmacology Fatty Acids, Omega-3 - therapeutic use Humans Humoral immunity Infection - drug therapy Infection - immunology Lipid microdomains N-3 polyunsaturated fatty acids
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