EPLIN: a fundamental actin regulator in cancer metastasis?

Treatment of malignant disease is of paramount importance in modern medicine. In 2012, it was estimated that 162,000 people died from cancer in the UK which illustrates a fundamental problem. Traditional treatments for cancer have various drawbacks, and this creates a considerable need for specific,...

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Veröffentlicht in:	Cancer and metastasis reviews 2015-12, Vol.34 (4), p.753-764
Hauptverfasser:	Collins, Ross J., Jiang, Wen G., Hargest, Rachel, Mason, Malcolm D., Sanders, Andrew J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Actin Actins - metabolism Adherens Junctions - metabolism Amino Acid Sequence Amino acids Binding Sites Biomedical and Life Sciences Biomedicine Breast Neoplasms - pathology Cancer Cancer Research Care and treatment Cell Division - physiology Cell Movement Cytoskeletal Proteins - metabolism Development and progression Female Gene Expression Regulation, Neoplastic Humans Male Metastasis Molecular Sequence Data Muscle proteins Neoplasm Metastasis - pathology Neoplasm Proteins - metabolism Neovascularization, Pathologic - pathology Non-Thematic Review Oncology Prostatic Neoplasms - pathology Protein Binding Signal Transduction
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