Autocrine Human Urotensin II Enhances Macrophage-Derived Foam Cell Formation in Transgenic Rabbits

Circulating urotensin II (UII) is involved in the development of atherosclerosis. However, the role of autocrine UII in the development of atherosclerosis remains unclear. Here, we tested the hypothesis that autocrine UII would promote atherosclerosis. Transgenic rabbits were created as a model to s...

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Veröffentlicht in:	BioMed research international 2015-01, Vol.2015 (2015), p.1-8
Hauptverfasser:	Fan, Jianglin, Liu, Enqi, Wang, Rong, Bai, Liang, Cheng, Daxing, Sun, Lijing, Wang, Xiaojing, Gao, Shoucui, Li, Yafeng, Zhao, Sihai, Guan, Hua
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Animals, Genetically Modified Atherosclerosis Atherosclerosis - metabolism Blood Glucose - analysis Blood pressure Body Weight Cholesterol Cholesterol - blood Cytokines Deoxyribonucleic acid DNA Foam Cells - cytology Genetic testing Growth hormones Health aspects Humans Macrophages Male Physiological aspects Plasma Rabbits Rodents Urotensins - genetics Urotensins - metabolism
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