Renal Mechanisms of Association between Fibroblast Growth Factor 1 and Blood Pressure

The fibroblast growth factor 1 (FGF1) gene is expressed primarily in the kidney and may contribute to hypertension. However, the biologic mechanisms underlying the association between FGF1 and BP regulation remain unknown. We report that the major allele of FGF1 single nucleotide polymorphism rs1525...

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Veröffentlicht in:	Journal of the American Society of Nephrology 2015-12, Vol.26 (12), p.3151-3160
Hauptverfasser:	Tomaszewski, Maciej, Eales, James, Denniff, Matthew, Myers, Stephen, Chew, Guat Siew, Nelson, Christopher P, Christofidou, Paraskevi, Desai, Aishwarya, Büsst, Cara, Wojnar, Lukasz, Musialik, Katarzyna, Jozwiak, Jacek, Debiec, Radoslaw, Dominiczak, Anna F, Navis, Gerjan, van Gilst, Wiek H, van der Harst, Pim, Samani, Nilesh J, Harrap, Stephen, Bogdanski, Pawel, Zukowska-Szczechowska, Ewa, Charchar, Fadi J
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Blood Pressure - genetics Clinical Research Female Fibroblast Growth Factor 1 - genetics Humans Hypertension - genetics Intracellular Signaling Peptides and Proteins - genetics Kidney - chemistry Male Middle Aged Minor Histocompatibility Antigens Neprilysin - genetics Polymorphism, Single Nucleotide Protein Serine-Threonine Kinases - genetics Receptor-Like Protein Tyrosine Phosphatases, Class 3 - genetics Renin - genetics RNA, Messenger - analysis Signal Transduction - genetics Solute Carrier Family 12, Member 3 - genetics WNK Lysine-Deficient Protein Kinase 1 Young Adult
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