The multifaceted roles of the HORMA domain in cellular signaling

The HORMA domain is a multifunctional protein-protein interaction module found in diverse eukaryotic signaling pathways including the spindle assembly checkpoint, numerous DNA recombination/repair pathways, and the initiation of autophagy. In all of these pathways, HORMA domain proteins occupy key s...

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Veröffentlicht in:	The Journal of cell biology 2015-11, Vol.211 (4), p.745-755
Hauptverfasser:	Rosenberg, Scott C, Corbett, Kevin D
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Autophagy Deoxyribonucleic acid DNA DNA-Binding Proteins - chemistry DNA-Binding Proteins - physiology DNA-Directed DNA Polymerase - chemistry DNA-Directed DNA Polymerase - physiology Eukaryotes Humans M Phase Cell Cycle Checkpoints Mad2 Proteins - chemistry Mad2 Proteins - physiology Protein Interaction Domains and Motifs Proteins Reviews RNA-protein interactions Saccharomyces cerevisiae Proteins - chemistry Saccharomyces cerevisiae Proteins - physiology Signal Transduction Structural Homology, Protein
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