Lipidomic Profiling of Liver Tissue from Obesity-Prone and Obesity-Resistant Mice Fed a High Fat Diet

Obesity is a multifactorial health problem resulting from genetic, environmental and behavioral factors. A particularly interesting aspect of obesity is the differences observed in response to the same high-fat diet (HFD). In this study, we performed lipidomic profiling on livers from HFD-fed C57BL/...

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Veröffentlicht in:	Scientific reports 2015-11, Vol.5 (1), p.16984-16984, Article 16984
Hauptverfasser:	Nam, Miso, Choi, Myung-Sook, Jung, Sunhee, Jung, Youngae, Choi, Ji-Young, Ryu, Do Hyun, Hwang, Geum-Sook
Format:	Artikel
Sprache:	eng
Schlagworte:	631/1647/296 631/45/320 631/45/608 64/60 Animals ATP Binding Cassette Transporter 1 - genetics ATP Binding Cassette Transporter 1 - metabolism Cholesterol Cholesterol - metabolism Chromatography, High Pressure Liquid Diet Diet, High-Fat - adverse effects Gene Expression Glucose - metabolism High fat diet Humanities and Social Sciences Insulin Insulin - metabolism Leptin Leptin - metabolism Lipid metabolism Lipid Metabolism - genetics Liquid chromatography Liver Liver - metabolism Liver - pathology Male Mass spectrometry Mass spectroscopy Metabolome - genetics Mice Mice, Inbred C57BL Mice, Obese multidisciplinary Obesity Obesity - etiology Obesity - genetics Obesity - metabolism Obesity - pathology Phosphocholine Phosphorylcholine - metabolism Principal Component Analysis Rodents Scavenger receptors Scavenger Receptors, Class B - genetics Scavenger Receptors, Class B - metabolism Science Species Specificity Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization Triglycerides - metabolism
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