Activated cytotoxic lymphocytes promote tumor progression by increasing the ability of 3LL tumor cells to mediate MDSC chemoattraction via Fas signaling

The Fas/FasL system transmits intracellular apoptotic signaling, inducing cell apoptosis. However, Fas signaling also exerts non-apoptotic functions in addition to inducing tumor cell apoptosis. For example, Fas signaling induces lung cancer tumor cells to produce prostaglandin E2 (PGE2) and recruit...

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Veröffentlicht in:Cellular & molecular immunology 2015-01, Vol.12 (1), p.66-76
Hauptverfasser: Yang, Fei, Wei, Yinxiang, Cai, Zhijian, Yu, Lei, Jiang, Lingling, Zhang, Chengyan, Yan, Huanmiao, Wang, Qingqing, Cao, Xuetao, Liang, Tingbo, Wang, Jianli
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Sprache:eng
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