The Immunopharmaceutical Effects and Mechanisms of Herb Medicine
In recent years, studies on evaluation of the therapeutic and toxic activity of herbal medicinal products became available and popular. The advances in modern biotechnology have led to discovery of many new active constituents. However, it is a constant challenge to establish the pharmacological bas...
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| Veröffentlicht in: | Cellular & molecular immunology 2008-02, Vol.5 (1), p.23-31 |
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| creator | Huang, Chien-Fu Lin, Shih-Shen Liao, Pao-Hsin Young, Su-Chung Yang, Chi-Chiang |
| description | In recent years, studies on evaluation of the therapeutic and toxic activity of herbal medicinal products became available and popular. The advances in modern biotechnology have led to discovery of many new active constituents. However, it is a constant challenge to establish the pharmacological basis for efficacy and safety of herbal medicinal products. A better understanding of the effects and bioavailability of phytopharmaceuticals can help in discovering suitable and rational therapies. In this review, we present the bioavailability studies in immune system that has been conducted for some of the more important or widely used phytopharmaceuticals. Furthermore, various new drug targets worthy of using for drug development in immunomodulating herbal medicine area and their regulatory mechanisms are also discussed. Adverse effects, drug interactions, and contraindications are also discussed which show that caution should be exercised when combining phytopharmaceuticals with chemically derived pharmaceutical components. Cellular ＆ Molecular Immunology. |
| doi_str_mv | 10.1038/cmi.2008.3 |
| format | Article |
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The advances in modern biotechnology have led to discovery of many new active constituents. However, it is a constant challenge to establish the pharmacological basis for efficacy and safety of herbal medicinal products. A better understanding of the effects and bioavailability of phytopharmaceuticals can help in discovering suitable and rational therapies. In this review, we present the bioavailability studies in immune system that has been conducted for some of the more important or widely used phytopharmaceuticals. Furthermore, various new drug targets worthy of using for drug development in immunomodulating herbal medicine area and their regulatory mechanisms are also discussed. Adverse effects, drug interactions, and contraindications are also discussed which show that caution should be exercised when combining phytopharmaceuticals with chemically derived pharmaceutical components. Cellular ＆ Molecular Immunology.</description><identifier>ISSN: 1672-7681</identifier><identifier>EISSN: 2042-0226</identifier><identifier>DOI: 10.1038/cmi.2008.3</identifier><identifier>PMID: 18318991</identifier><language>eng</language><publisher>London: Nature Publishing Group UK</publisher><subject>Antibodies ; Antibody Formation - drug effects ; Antioxidants - adverse effects ; Antioxidants - pharmacology ; Antioxidants - therapeutic use ; Apoptosis - drug effects ; Autoimmune Diseases - drug therapy ; Autoimmunity ; Bioavailability ; Biomedical and Life Sciences ; Biomedicine ; Biotechnology ; Contraindications ; Cytokines - metabolism ; Drug development ; Drugs, Chinese Herbal - adverse effects ; Drugs, Chinese Herbal - pharmacology ; Drugs, Chinese Herbal - therapeutic use ; Herbal medicine ; Humans ; Immune system ; Immune System - drug effects ; Immune System - immunology ; Immunology ; Infection - drug therapy ; Medical Microbiology ; Microbiology ; Neoplasms - drug therapy ; Phytotherapy - adverse effects ; Plants, Medicinal ; Review ; T-Lymphocytes - drug effects ; T-Lymphocytes - immunology ; T-Lymphocytes - metabolism ; Therapeutic targets ; Vaccine ; 淋巴球 ; 自身免疫系统</subject><ispartof>Cellular & molecular immunology, 2008-02, Vol.5 (1), p.23-31</ispartof><rights>The Chinese Society of Immunology 2008</rights><rights>Copyright Nature Publishing Group Feb 2008</rights><rights>The Chinese Society of Immunology 2008.</rights><rights>Copyright © Wanfang Data Co. 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The advances in modern biotechnology have led to discovery of many new active constituents. However, it is a constant challenge to establish the pharmacological basis for efficacy and safety of herbal medicinal products. A better understanding of the effects and bioavailability of phytopharmaceuticals can help in discovering suitable and rational therapies. In this review, we present the bioavailability studies in immune system that has been conducted for some of the more important or widely used phytopharmaceuticals. Furthermore, various new drug targets worthy of using for drug development in immunomodulating herbal medicine area and their regulatory mechanisms are also discussed. Adverse effects, drug interactions, and contraindications are also discussed which show that caution should be exercised when combining phytopharmaceuticals with chemically derived pharmaceutical components. Cellular ＆ Molecular Immunology.</description><subject>Antibodies</subject><subject>Antibody Formation - drug effects</subject><subject>Antioxidants - adverse effects</subject><subject>Antioxidants - pharmacology</subject><subject>Antioxidants - therapeutic use</subject><subject>Apoptosis - drug effects</subject><subject>Autoimmune Diseases - drug therapy</subject><subject>Autoimmunity</subject><subject>Bioavailability</subject><subject>Biomedical and Life Sciences</subject><subject>Biomedicine</subject><subject>Biotechnology</subject><subject>Contraindications</subject><subject>Cytokines - metabolism</subject><subject>Drug development</subject><subject>Drugs, Chinese Herbal - adverse effects</subject><subject>Drugs, Chinese Herbal - pharmacology</subject><subject>Drugs, Chinese Herbal - therapeutic use</subject><subject>Herbal medicine</subject><subject>Humans</subject><subject>Immune system</subject><subject>Immune System - drug effects</subject><subject>Immune System - immunology</subject><subject>Immunology</subject><subject>Infection - 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Hong Kong</collection><collection>WANFANG Data Centre</collection><collection>Wanfang Data Journals</collection><collection>万方数据期刊 - 香港版</collection><collection>China Online Journals (COJ)</collection><collection>China Online Journals (COJ)</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Cellular & molecular immunology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Huang, Chien-Fu</au><au>Lin, Shih-Shen</au><au>Liao, Pao-Hsin</au><au>Young, Su-Chung</au><au>Yang, Chi-Chiang</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The Immunopharmaceutical Effects and Mechanisms of Herb Medicine</atitle><jtitle>Cellular & molecular immunology</jtitle><stitle>Cell Mol Immunol</stitle><addtitle>Cellular ＆ Molecular Immunology</addtitle><date>2008-02-01</date><risdate>2008</risdate><volume>5</volume><issue>1</issue><spage>23</spage><epage>31</epage><pages>23-31</pages><issn>1672-7681</issn><eissn>2042-0226</eissn><abstract>In recent years, studies on evaluation of the therapeutic and toxic activity of herbal medicinal products became available and popular. The advances in modern biotechnology have led to discovery of many new active constituents. However, it is a constant challenge to establish the pharmacological basis for efficacy and safety of herbal medicinal products. A better understanding of the effects and bioavailability of phytopharmaceuticals can help in discovering suitable and rational therapies. In this review, we present the bioavailability studies in immune system that has been conducted for some of the more important or widely used phytopharmaceuticals. Furthermore, various new drug targets worthy of using for drug development in immunomodulating herbal medicine area and their regulatory mechanisms are also discussed. Adverse effects, drug interactions, and contraindications are also discussed which show that caution should be exercised when combining phytopharmaceuticals with chemically derived pharmaceutical components. Cellular ＆ Molecular Immunology.</abstract><cop>London</cop><pub>Nature Publishing Group UK</pub><pmid>18318991</pmid><doi>10.1038/cmi.2008.3</doi><tpages>9</tpages><oa>free_for_read</oa></addata></record> |
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| ispartof | Cellular & molecular immunology, 2008-02, Vol.5 (1), p.23-31 |
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| subjects | Antibodies Antibody Formation - drug effects Antioxidants - adverse effects Antioxidants - pharmacology Antioxidants - therapeutic use Apoptosis - drug effects Autoimmune Diseases - drug therapy Autoimmunity Bioavailability Biomedical and Life Sciences Biomedicine Biotechnology Contraindications Cytokines - metabolism Drug development Drugs, Chinese Herbal - adverse effects Drugs, Chinese Herbal - pharmacology Drugs, Chinese Herbal - therapeutic use Herbal medicine Humans Immune system Immune System - drug effects Immune System - immunology Immunology Infection - drug therapy Medical Microbiology Microbiology Neoplasms - drug therapy Phytotherapy - adverse effects Plants, Medicinal Review T-Lymphocytes - drug effects T-Lymphocytes - immunology T-Lymphocytes - metabolism Therapeutic targets Vaccine 淋巴球 自身免疫系统 |
| title | The Immunopharmaceutical Effects and Mechanisms of Herb Medicine |
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