Sex differences in the expression of lung inflammatory mediators in response to ozone

Sex differences in the incidence of respiratory diseases have been reported. Women are more susceptible to inflammatory lung disease induced by air pollution and show worse adverse pulmonary health outcomes than men. However, the mechanisms underlying these differences remain unknown. In the present...

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Veröffentlicht in:	American journal of physiology. Lung cellular and molecular physiology 2015-11, Vol.309 (10), p.L1150-L1163
Hauptverfasser:	Cabello, Noe, Mishra, Vikas, Sinha, Utkarshna, DiAngelo, Susan L, Chroneos, Zissis C, Ekpa, Ndifreke A, Cooper, Timothy K, Caruso, Carla R, Silveyra, Patricia
Format:	Artikel
Sprache:	eng
Schlagworte:	Air Pollutants - toxicity Animals Call for Papers Capillary Permeability Enzymes Female Gender differences Gene expression Inflammation Inflammation Mediators - metabolism Interleukins - genetics Interleukins - metabolism Lung - immunology Lung - metabolism Lung - pathology Lungs Male Mice, Inbred C57BL Neutrophil Infiltration Oxidative Stress Ozone Ozone - toxicity Pneumonia - chemically induced Pneumonia - immunology Pneumonia - metabolism Receptors, Pattern Recognition - genetics Receptors, Pattern Recognition - metabolism Sex Characteristics STAT3 Transcription Factor - metabolism Transcription Factors - genetics Transcription Factors - metabolism Transcriptome
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