Polarized ATP distribution in urothelial mucosal and serosal space is differentially regulated by stretch and ectonucleotidases

Purinergic signaling is a major pathway in regulating bladder function, and mechanical force stimulates urothelial ATP release, which plays an important role in bladder mechanotransduction. Although urothelial ATP release was first reported almost 20 years ago, the way in which release is regulated...

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Veröffentlicht in:	American journal of physiology. Renal physiology 2015-11, Vol.309 (10), p.F864-F872
1. Verfasser:	Yu, Weiqun
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine triphosphatase Adenosine Triphosphatases - metabolism Adenosine Triphosphate - metabolism Animals Bladder Calcium - metabolism Enzymes Female Kinetics Mechanotransduction, Cellular - physiology Mucous Membrane - metabolism Rabbits Stress, Mechanical Urinary Bladder - metabolism Urothelium - metabolism
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