Absence of RIPK3 predicts necroptosis resistance in malignant melanoma

Acquired or intrinsic resistance to apoptotic and necroptotic stimuli is considered a major hindrance of therapeutic success in malignant melanoma. Inhibitor of apoptosis proteins (IAPs) are important regulators of apoptotic and necroptotic cell death mediated by numerous cell death signalling platf...

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Veröffentlicht in:	Cell death & disease 2015-09, Vol.6 (9), p.e1884-e1884
Hauptverfasser:	Geserick, P, Wang, J, Schilling, R, Horn, S, Harris, P A, Bertin, J, Gough, P J, Feoktistova, M, Leverkus, M
Format:	Artikel
Sprache:	eng
Schlagworte:	38 38/90 631/80/82/2344 631/80/86 692/699/67/1059/99 692/699/67/1813/1634 Antibodies Apoptosis Biochemistry Biomedical and Life Sciences Cell Biology Cell Culture Humans Immunology Life Sciences Melanoma - genetics Necrosis - enzymology Necrosis - metabolism Original original-article Receptor-Interacting Protein Serine-Threonine Kinases - genetics Receptor-Interacting Protein Serine-Threonine Kinases - metabolism
Online-Zugang:	Volltext
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