Dormant non-culturable Mycobacterium tuberculosis retains stable low-abundant mRNA

Dormant Mycobacterium tuberculosis bacilli are believed to play an important role in latent tuberculosis infection. Previously, we have demonstrated that cultivation of M. tuberculosis in K(+)-deficient medium resulted in generation of dormant cells. These bacilli were non-culturable on solid media...

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Veröffentlicht in:	BMC genomics 2015-11, Vol.16 (943), p.954-954, Article 954
Hauptverfasser:	Ignatov, Dmitriy V, Salina, Elena G, Fursov, Mikhail V, Skvortsov, Timofey A, Azhikina, Tatyana L, Kaprelyants, Arseny S
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Bacterial Proteins - genetics Culture Techniques Gene Expression Profiling Genomics Messenger RNA Models, Biological Mycobacterium tuberculosis Mycobacterium tuberculosis - cytology Mycobacterium tuberculosis - drug effects Mycobacterium tuberculosis - genetics Mycobacterium tuberculosis - growth & development Phenotype Potassium - pharmacology Ribosomal RNA RNA Stability RNA, Bacterial - chemistry RNA, Bacterial - genetics RNA, Bacterial - metabolism RNA, Messenger - chemistry RNA, Messenger - genetics RNA, Messenger - metabolism RNA, Ribosomal, 23S - chemistry RNA, Ribosomal, 23S - genetics RNA, Ribosomal, 23S - metabolism Sequence Analysis, RNA Tuberculosis
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