Encephalomyocarditis Virus 3C Protease Relieves TRAF Family Member-associated NF-κB Activator (TANK) Inhibitory Effect on TRAF6-mediated NF-κB Signaling through Cleavage of TANK

TRAF family member-associated NF-κB activator (TANK) is a negative regulator of canonical NF-κB signaling in the Toll-like receptor- and B-cell receptor-mediated signaling pathways. However, functions of TANK in viral infection-mediated NF-κB activation remain unclear. Here, we reported that TANK wa...

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Veröffentlicht in:The Journal of biological chemistry 2015-11, Vol.290 (46), p.27618-27632
Hauptverfasser: Huang, Li, Liu, Qinfang, Zhang, Lijie, Zhang, Quan, Hu, Liang, Li, Changyao, Wang, Shengnan, Li, Jiangnan, Zhang, Yuanfeng, Yu, Huibin, Wang, Yan, Zhong, Zhaohua, Xiong, Tao, Xia, Xueshan, Wang, Xiaojun, Yu, Li, Deng, Guohua, Cai, Xuehui, Cui, Shangjin, Weng, Changjiang
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Sprache:eng
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