Breast Cancer Metabolism and Mitochondrial Activity: The Possibility of Chemoprevention with Metformin

Metabolic reprogramming refers to the ability of cancer cells to alter their metabolism in order to support the increased energy request due to continuous growth, rapid proliferation, and other characteristics typical of neoplastic cells. It has long been believed that the increase of metabolic requ...

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Veröffentlicht in:	BioMed research international 2015-01, Vol.2015 (2015), p.1-9
Hauptverfasser:	Cazzaniga, Massimiliano, Bonanni, Bernardo
Format:	Artikel
Sprache:	eng
Schlagworte:	Breast cancer Breast Neoplasms - metabolism Breast Neoplasms - prevention & control Cancer Cancer therapies Cell Proliferation - drug effects Cooperation Disease prevention Drug resistance Female Glucose Humans Hypoxia Metabolism Metformin Metformin - therapeutic use Mitochondria Mitochondria - metabolism Oncology, Experimental Phosphorylation Physiological aspects Prevention Review
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