Bmp2 conditional knockout in osteoblasts and endothelial cells does not impair bone formation after injury or mechanical loading in adult mice

Abstract Post-natal osteogenesis after mechanical trauma or stimulus occurs through either endochondral healing, intramembranous healing or lamellar bone formation. Bone morphogenetic protein 2 (BMP2) is up-regulated in each of these osteogenic processes and is expressed by a variety of cells includ...

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Veröffentlicht in:	Bone (New York, N.Y.) N.Y.), 2015-12, Vol.81, p.533-543
Hauptverfasser:	McBride-Gagyi, Sarah Howe, McKenzie, Jennifer A, Buettmann, Evan G, Gardner, Michael J, Silva, Matthew J
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals BMP2 Bone homeostasis Bone injury Bone Morphogenetic Protein 2 - deficiency Bone Morphogenetic Protein 2 - genetics Bone Morphogenetic Protein 2 - physiology Endothelial Cells - physiology Facture healing Female Fracture Healing - genetics Fracture Healing - physiology Fractures, Stress - genetics Fractures, Stress - pathology Fractures, Stress - physiopathology Gene Expression Male Mice Mice, Knockout Orthopedics Osteoblasts Osteoblasts - physiology Osteogenesis - genetics Osteogenesis - physiology Stress, Mechanical
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