T Cell Responses against Mycobacterial Lipids and Proteins Are Poorly Correlated in South African Adolescents

Human T cells are activated by both peptide and nonpeptide Ags produced by Mycobacterium tuberculosis. T cells recognize cell wall lipids bound to CD1 molecules, but effector functions of CD1-reactive T cells have not been systematically assessed in M. tuberculosis-infected humans. It is also not kn...

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