Plakoglobin expression in fibroblasts and its role in idiopathic pulmonary fibrosis

Idiopathic pulmonary fibrosis (IPF) is an interstitial fibrotic lung disease of unknown origin and without effective therapy characterized by deposition of extracellular matrix by activated fibroblasts in the lung. Fibroblast activation in IPF is associated with Wnt/β-catenin signaling, but little i...

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Veröffentlicht in:	BMC pulmonary medicine 2015-11, Vol.15 (134), p.140-140, Article 140
Hauptverfasser:	Matthes, Stephanie A, LaRouere, Thomas J, Horowitz, Jeffrey C, White, Eric S
Format:	Artikel
Sprache:	eng
Schlagworte:	Apoptosis - genetics Blotting, Western Care and treatment Case-Control Studies Cell Adhesion - genetics Cell Proliferation - genetics Cells, Cultured Complications and side effects Desmoplakins - genetics Desmoplakins - metabolism Fibroblasts Fibroblasts - metabolism Fibronectins - metabolism gamma Catenin Gene Knockdown Techniques Humans Idiopathic Pulmonary Fibrosis - genetics Idiopathic Pulmonary Fibrosis - metabolism Influence Mortality Pulmonary fibrosis Pulmonology Real-Time Polymerase Chain Reaction Risk factors RNA, Messenger - metabolism
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