Secondary Analyses of the Effects of Lutein/Zeaxanthin on Age-Related Macular Degeneration Progression AREDS2 Report No.3
The Age-Related Eye Disease Study (AREDS) formulation for treatment of age-related macular degeneration contains vitamins C, E, beta-carotene and zinc with copper. Age-Related Eye Disease Study 2 (AREDS2) assessed the value of substituting lutein/zeaxanthin in the AREDS formulation because of the de...
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Veröffentlicht in: | JAMA ophthalmology 2014-02, Vol.132 (2), p.142-149 |
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creator | Chew, Emily Y. Clemons, Traci E. SanGiovanni, John Paul Danis, Ronald P Ferris, Frederick L. Elman, Michael J. Antoszyk, Andrew Ruby, Alan Orth, David Bressler, Susan B. Fish, Gary Hubbard, Baker Klein, Michael Chandra, Suresh Blodi, Barbara Domalpally, Amitha Friberg, Thomas Wong, Wai Rosenfeld, Philip Agron, Elvira Toth, Cynthia Bernstein, Paul Sperduto, Robert |
description | The Age-Related Eye Disease Study (AREDS) formulation for treatment of age-related macular degeneration contains vitamins C, E, beta-carotene and zinc with copper. Age-Related Eye Disease Study 2 (AREDS2) assessed the value of substituting lutein/zeaxanthin in the AREDS formulation because of the demonstrated risk of lung cancer from beta-carotene in smokers and former smokers. As previously reported in a secondary analysis, AREDS2 participants taking lutein/zeaxanthin with or without omega-3 long-chain polyunsaturated fatty 3 acids had a slightly lower progression rate to late AMD than participants not taking lutein/zeaxanthin. |
doi_str_mv | 10.1001/jamaophthalmol.2013.7376 |
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title | Secondary Analyses of the Effects of Lutein/Zeaxanthin on Age-Related Macular Degeneration Progression AREDS2 Report No.3 |
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