Secondary Analyses of the Effects of Lutein/Zeaxanthin on Age-Related Macular Degeneration Progression AREDS2 Report No.3

The Age-Related Eye Disease Study (AREDS) formulation for treatment of age-related macular degeneration contains vitamins C, E, beta-carotene and zinc with copper. Age-Related Eye Disease Study 2 (AREDS2) assessed the value of substituting lutein/zeaxanthin in the AREDS formulation because of the de...

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Veröffentlicht in:JAMA ophthalmology 2014-02, Vol.132 (2), p.142-149
Hauptverfasser: Chew, Emily Y., Clemons, Traci E., SanGiovanni, John Paul, Danis, Ronald P, Ferris, Frederick L., Elman, Michael J., Antoszyk, Andrew, Ruby, Alan, Orth, David, Bressler, Susan B., Fish, Gary, Hubbard, Baker, Klein, Michael, Chandra, Suresh, Blodi, Barbara, Domalpally, Amitha, Friberg, Thomas, Wong, Wai, Rosenfeld, Philip, Agron, Elvira, Toth, Cynthia, Bernstein, Paul, Sperduto, Robert
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container_end_page 149
container_issue 2
container_start_page 142
container_title JAMA ophthalmology
container_volume 132
creator Chew, Emily Y.
Clemons, Traci E.
SanGiovanni, John Paul
Danis, Ronald P
Ferris, Frederick L.
Elman, Michael J.
Antoszyk, Andrew
Ruby, Alan
Orth, David
Bressler, Susan B.
Fish, Gary
Hubbard, Baker
Klein, Michael
Chandra, Suresh
Blodi, Barbara
Domalpally, Amitha
Friberg, Thomas
Wong, Wai
Rosenfeld, Philip
Agron, Elvira
Toth, Cynthia
Bernstein, Paul
Sperduto, Robert
description The Age-Related Eye Disease Study (AREDS) formulation for treatment of age-related macular degeneration contains vitamins C, E, beta-carotene and zinc with copper. Age-Related Eye Disease Study 2 (AREDS2) assessed the value of substituting lutein/zeaxanthin in the AREDS formulation because of the demonstrated risk of lung cancer from beta-carotene in smokers and former smokers. As previously reported in a secondary analysis, AREDS2 participants taking lutein/zeaxanthin with or without omega-3 long-chain polyunsaturated fatty 3 acids had a slightly lower progression rate to late AMD than participants not taking lutein/zeaxanthin.
doi_str_mv 10.1001/jamaophthalmol.2013.7376
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title Secondary Analyses of the Effects of Lutein/Zeaxanthin on Age-Related Macular Degeneration Progression AREDS2 Report No.3
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