Complexation Hydrogels as Oral Delivery Vehicles of Therapeutic Antibodies: An in Vitro and ex Vivo Evaluation of Antibody Stability and Bioactivity

Oral administration of monoclonal antibodies (mAbs) may enable the localized treatment of infections or other conditions in the gastrointestinal tract (GI) as well as systemic diseases. As with the development of oral protein biotherapeutics, one of the most challenging tasks in antibody therapies i...

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Veröffentlicht in:	Industrial & engineering chemistry research 2015-10, Vol.54 (42), p.10197-10205
Hauptverfasser:	Carrillo-Conde, Brenda R, Brewer, Erik, Lowman, Anthony, Peppas, Nicholas A
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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