Mechanisms underlying the activity-dependent regulation of locomotor network performance by the Na+ pump

Activity-dependent modification of neural network output usually results from changes in neurotransmitter release and/or membrane conductance. In Xenopus frog tadpoles, spinal locomotor network output is adapted by an ultraslow afterhyperpolarization (usAHP) mediated by an increase in Na + pump curr...

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Veröffentlicht in:	Scientific reports 2015-11, Vol.5 (1), p.16188-16188, Article 16188
Hauptverfasser:	Zhang, Hong-Yan, Picton, Laurence, Li, Wen-Chang, Sillar, Keith T.
Format:	Artikel
Sprache:	eng
Schlagworte:	631/378/2632/1823 631/378/2632/2633 631/378/3920 64/114 9/30 9/74 Action Potentials - physiology Afterhyperpolarization Animals Central pattern generator Depolarization Excitatory Postsynaptic Potentials - physiology Firing pattern Firing rate Humanities and Social Sciences Hyperpolarization Inactivation Interneurons Interneurons - metabolism Interneurons - physiology Locomotion - physiology Membrane conductance Monensin multidisciplinary Na+/H+-exchanging ATPase Nerve Net - physiology Neural Inhibition - physiology Neural networks Neurons - metabolism Neurons - physiology Neurotransmitter release Ouabain Periodicity Science Sodium-Potassium-Exchanging ATPase - metabolism Spinal Cord - metabolism Spinal Cord - physiology Swimming Swimming - physiology Synaptic Transmission - physiology Xenopus laevis - metabolism Xenopus laevis - physiology
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