Effects of Anesthesia on BOLD Signal and Neuronal Activity in the Somatosensory Cortex

Most functional magnetic resonance imaging (fMRI) animal studies rely on anesthesia, which can induce a variety of drug-dependent physiological changes, including depression of neuronal activity and cerebral metabolism as well as direct effects on the vasculature. The goal of this study was to chara...

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Veröffentlicht in:	Journal of cerebral blood flow and metabolism 2015-11, Vol.35 (11), p.1819-1826
Hauptverfasser:	Aksenov, Daniil P, Li, Limin, Miller, Michael J, Iordanescu, Gheorghe, Wyrwicz, Alice M
Format:	Artikel
Sprache:	eng
Schlagworte:	Anesthesia Anesthetics, Inhalation - pharmacology Anesthetics, Intravenous - pharmacology Animals Brain Mapping - methods Evoked Potentials - drug effects Female Fentanyl - pharmacology Isoflurane - pharmacology Magnetic Resonance Imaging - methods Neurons - drug effects Original Oxygen - blood Physical Stimulation Rabbits Somatosensory Cortex - anatomy & histology Somatosensory Cortex - drug effects Vibrissae - drug effects Vibrissae - innervation
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