Bub1 is required for maintaining cancer stem cells in breast cancer cell lines

Breast cancer is a leading cause of death among women worldwide due to therapeutic resistance and cancer recurrence. Cancer stem cells are believed to be responsible for resistance and recurrence. Many efforts to overcome resistance and recurrence by regulating cancer stem cells are ongoing. Bub1 (B...

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Veröffentlicht in:	Scientific reports 2015-11, Vol.5 (1), p.15993-15993, Article 15993
Hauptverfasser:	Han, Jeong Yoon, Han, Yu Kyeong, Park, Ga-Young, Kim, Sung Dae, Geun Lee, Chang
Format:	Artikel
Sprache:	eng
Schlagworte:	13/109 13/31 13/95 631/67/71 631/80/641/1655 Animals Benzimidazoles Breast cancer Breast Neoplasms - genetics Budding Cell Line, Tumor Chromosome Segregation - genetics Female Humanities and Social Sciences Humans Mice Mice, Inbred BALB C Mice, Nude multidisciplinary Neoplasm Recurrence, Local - genetics Neoplastic Stem Cells - metabolism Protein-Serine-Threonine Kinases - genetics Protein-serine/threonine kinase RNA, Small Interfering - genetics Science Stem cell transplantation Stem cells Tumor cell lines Xenografts
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