Cytotoxic and apoptotic effects of menadione on rat hepatocellular carcinoma cells

Hepatocellular carcinoma (HCC) is one of the most common cancers, which may lead to death. Menadione shows cytotoxic activity thought affecting redox cycling in cancer cells. The aim of the present study was to investigate the effects of menadione on rat hepatocellular carcinoma (H4IIE) cell morphol...

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Veröffentlicht in:	Cytotechnology (Dordrecht) 2015-12, Vol.67 (6), p.1003-1009
Hauptverfasser:	Oztopcu-Vatan, Pinar, Sayitoglu, Muge, Gunindi, Melek, Inan, Emine
Format:	Artikel
Sprache:	eng
Schlagworte:	Apoptosis Biochemistry Biomedicine Biotechnology Cancer therapies Cell cycle Cell death Cell fate Cell morphology Cell viability Chemistry Chemistry and Materials Science Cytology Cytotoxicity DNA damage DNA repair Hepatitis C Hepatocellular carcinoma Liver cancer Medical prognosis Menadione Morphology Original Research Poly(ADP-ribose) polymerase Real time Redox properties Toxicity Variance analysis
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