Stem cell transplantation therapy in Parkinson’s disease

Ineffective therapeutic treatments and inadequate repair ability in the central nervous system are disturbing problems for several neurological diseases. Fortunately, the development of clinically applicable populations of stem cells has provided an avenue to overcome the failure of endogenous repai...

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Veröffentlicht in:SpringerPlus 2015-10, Vol.4 (1), p.597-597, Article 597
Hauptverfasser: Fu, Mu-Hui, Li, Chia-Ling, Lin, Hsiu-Lien, Chen, Pei-Chun, Calkins, Marcus J., Chang, Yu-Fan, Cheng, Pei-Hsun, Yang, Shang-Hsun
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container_title SpringerPlus
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creator Fu, Mu-Hui
Li, Chia-Ling
Lin, Hsiu-Lien
Chen, Pei-Chun
Calkins, Marcus J.
Chang, Yu-Fan
Cheng, Pei-Hsun
Yang, Shang-Hsun
description Ineffective therapeutic treatments and inadequate repair ability in the central nervous system are disturbing problems for several neurological diseases. Fortunately, the development of clinically applicable populations of stem cells has provided an avenue to overcome the failure of endogenous repair systems and substitute new cells into the damaged brain. However, there are still several existing obstacles to translating into clinical application. Here we review the stem-cell based therapies for Parkinson’s disease and discuss the potential advantages and drawbacks. We hope this review may provide suggestions for viable strategies to overcome the current technical and biological issues associated with the application of stem cells in Parkinson’s disease.
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source Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central Open Access; PubMed Central; Springer Nature OA/Free Journals; Free Full-Text Journals in Chemistry
subjects Humanities and Social Sciences
Medicine
multidisciplinary
Parkinson's disease
Review
Science
Science (multidisciplinary)
title Stem cell transplantation therapy in Parkinson’s disease
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