Apoptosis and acute kidney injury

Improved mechanistic understanding of renal cell death in acute kidney injury (AKI) has generated new therapeutic targets. Clearly, the classic lesion of acute tubular necrosis is not adequate to describe the consequences of renal ischemia, nephrotoxin exposure, or sepsis on glomerular filtration ra...

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Veröffentlicht in:	Kidney international 2011-07, Vol.80 (1), p.29-40
Hauptverfasser:	Havasi, Andrea, Borkan, Steven C
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute Kidney Injury - etiology Acute Kidney Injury - pathology Acute Kidney Injury - physiopathology Acute Kidney Injury - therapy acute renal failure Animals Apoptosis - physiology Biological and medical sciences cell biology and structure cell death cell signaling cell survival Glycogen Synthase Kinase 3 - metabolism Glycogen Synthase Kinase 3 beta Humans Ischemia - pathology Kidney - blood supply Kidney - pathology Kidney - physiopathology Kidneys Medical sciences Models, Biological Nephrology. Urinary tract diseases Nephropathies. Renovascular diseases. Renal failure Proto-Oncogene Proteins c-akt - metabolism Proto-Oncogene Proteins c-bcl-2 - metabolism Renal failure Shock, Septic - complications Shock, Septic - pathology Signal Transduction Stress, Physiological Urinary system involvement in other diseases. Miscellaneous
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