Direct effects of HP Acthar Gel on human B lymphocyte activation in vitro

Both clinical experience and experimental evidence have suggested that Adrenocorticotropic hormone (ACTH) might directly exert immunomodulatory effects not dependent on adrenal steroidogenesis. The direct effects of H.P. Acthar Gel (Acthar), a repository preparation containing a porcine ACTH analogu...

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Veröffentlicht in:	Arthritis research & therapy 2015-10, Vol.17 (1), p.300-300, Article 300
Hauptverfasser:	Olsen, Nancy J, Decker, Dima A, Higgins, Paul, Becker, Patrice M, McAloose, Carl A, Benko, Ann L, Kovacs, William J
Format:	Artikel
Sprache:	eng
Schlagworte:	ACTH Adrenocorticotropic Hormone - analogs & derivatives Adrenocorticotropic Hormone - pharmacology Adult Analysis Animals B cells B-Lymphocytes - drug effects B-Lymphocytes - immunology Cell Proliferation - drug effects Cell Separation Cell Survival - drug effects Cytidine Deaminase - biosynthesis Female Flow Cytometry Health aspects Humans Immunoassay Immunoglobulin G In Vitro Techniques Interleukins Lymphocyte Activation - drug effects Male Medical research Medicine, Experimental Messenger RNA Pharmaceutical industry Physiological aspects Real-Time Polymerase Chain Reaction Reverse Transcriptase Polymerase Chain Reaction Swine
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