Effect of epidermal growth factor (EGF) on the phosphorylation of mitogen-activated protein kinase (MAPK) in the bovine oviduct in vitro: Alteration by heat stress

Epidermal growth factor (EGF) has been shown to be involved in control of the oviductal microenvironment. To elucidate the potential mechanisms responsible for the detrimental effect of heat stress and to identify the relation with the endocrine status, the effects of EGF on the level of phosphoryla...

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Veröffentlicht in:	Journal of Reproduction and Development 2015, Vol.61(5), pp.383-389
Hauptverfasser:	WIJAYAGUNAWARDANE, Missaka P.B., HAMBRUCH, Nina, HAEGER, Jan-Dirk, PFARRER, Christiane
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Bovine oviduct Cattle Cell culture Cell Proliferation - drug effects Cells, Cultured Epidermal growth factor Epidermal Growth Factor - genetics Epidermal Growth Factor - metabolism Female Fertile Period - drug effects Fertile Period - metabolism Follicular Phase - drug effects Follicular Phase - metabolism Heat stress Hot Temperature - adverse effects Humans Luteal Phase - drug effects Luteal Phase - metabolism MAP Kinase Signaling System - drug effects Mitogen-Activated Protein Kinases - antagonists & inhibitors Mitogen-Activated Protein Kinases - metabolism Mitogen-activated-protein kinase (MAPK) Mucous Membrane - cytology Mucous Membrane - drug effects Mucous Membrane - metabolism Original Oviducts - cytology Oviducts - drug effects Oviducts - metabolism Phosphorylation - drug effects Protein Kinase Inhibitors - pharmacology Protein Processing, Post-Translational - drug effects Receptor, Epidermal Growth Factor - agonists Receptor, Epidermal Growth Factor - metabolism Recombinant Proteins - metabolism Up-Regulation - drug effects
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