The Breadth of Expandable Memory CD8+ T Cells Inversely Correlates with Residual Viral Loads in HIV Elite Controllers

Previous studies have shown that elite controllers with minimal effector T cell responses harbor a low-frequency, readily expandable, highly functional, and broadly directed memory population. Here, we interrogated the in vivo relevance of this cell population by investigating whether the breadth of...

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Veröffentlicht in:Journal of virology 2015-11, Vol.89 (21), p.10735-10747
Hauptverfasser: Ndhlovu, Zaza M, Stampouloglou, Eleni, Cesa, Kevin, Mavrothalassitis, Orestes, Alvino, Donna Marie, Li, Jonathan Z, Wilton, Shannon, Karel, Daniel, Piechocka-Trocha, Alicja, Chen, Huabiao, Pereyra, Florencia, Walker, Bruce D
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Sprache:eng
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