Heterozygous FZ alpha 1 antitrypsin deficiency associated with severe emphysema and hepatic disease: case report and family study

A patient with advanced emphysema and cor pulmonale had the changes of alpha 1 antitrypsin deficiency in a liver biopsy specimen and was shown to have the phenotype PiFZ. This case supports the contention that the F allele of alpha 1 antitrypsin predisposes to the development of emphysema, particula...

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Veröffentlicht in:	Thorax 1989-09, Vol.44 (9), p.758-759
Hauptverfasser:	Kelly, C P, Tyrrell, D N, McDonald, G S, Whitehouse, D B, Prichard, J S
Format:	Artikel
Sprache:	eng
Schlagworte:	alpha 1-Antitrypsin Deficiency Emphysema - complications Emphysema - genetics Female Humans Liver Diseases - complications Liver Diseases - genetics Middle Aged Pedigree Phenotype Pulmonary Heart Disease - complications
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