Association between shift work and the risk of death from biliary tract cancer in Japanese men
There is increasing evidence suggesting that shift work involving night work may increase cancer risk. We examined the association between working rotating shifts and the risk of death from biliary tract cancer among Japanese men who participated in the Japan Collaborative Cohort Study. Of the 46,39...
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| creator | Lin, Yingsong Nishiyama, Takeshi Kurosawa, Michiko Tamakoshi, Akiko Kubo, Tatsuhiko Fujino, Yoshihisa Kikuchi, Shogo |
| description | There is increasing evidence suggesting that shift work involving night work may increase cancer risk.
We examined the association between working rotating shifts and the risk of death from biliary tract cancer among Japanese men who participated in the Japan Collaborative Cohort Study. Of the 46,395 men recruited, 22,224 men aged 40-65 at baseline (1988-1990) who reported working full-time or were self-employed were included in the present analysis. The study subjects were followed through December 31, 2009. Information regarding occupation and lifestyle factors was collected using a self-administered questionnaire. Cox proportional hazard models were used to estimate the hazard ratio (HR) and 95 % confidence interval (CI) for the risk of death from biliary tract cancer in relation to shift work.
During a mean 17-year follow-up, we observed 94 biliary tract cancer deaths, including 23 deaths from gallbladder cancer and 71 deaths from extrahepatic bile duct cancer. Overall, shift work was associated with a statistically non-significant increase in the risk of biliary tract cancer, with an HR of 1.50 (95 % CI: 0.81-2.77), among rotating shift workers. When the analysis was limited to extrahepatic bile duct cancer, a significant association appeared, with a multivariable-adjusted HR of 1.93 (95 % CI: 1.00-3.72) for rotating shift workers.
Our data indicate that shift work may be associated with increased risk of death from extrahepatic bile duct cancer in this cohort of Japanese men. The association with gallbladder cancer remains unclear because of the small number of deaths. |
| doi_str_mv | 10.1186/s12885-015-1722-y |
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We examined the association between working rotating shifts and the risk of death from biliary tract cancer among Japanese men who participated in the Japan Collaborative Cohort Study. Of the 46,395 men recruited, 22,224 men aged 40-65 at baseline (1988-1990) who reported working full-time or were self-employed were included in the present analysis. The study subjects were followed through December 31, 2009. Information regarding occupation and lifestyle factors was collected using a self-administered questionnaire. Cox proportional hazard models were used to estimate the hazard ratio (HR) and 95 % confidence interval (CI) for the risk of death from biliary tract cancer in relation to shift work.
During a mean 17-year follow-up, we observed 94 biliary tract cancer deaths, including 23 deaths from gallbladder cancer and 71 deaths from extrahepatic bile duct cancer. Overall, shift work was associated with a statistically non-significant increase in the risk of biliary tract cancer, with an HR of 1.50 (95 % CI: 0.81-2.77), among rotating shift workers. When the analysis was limited to extrahepatic bile duct cancer, a significant association appeared, with a multivariable-adjusted HR of 1.93 (95 % CI: 1.00-3.72) for rotating shift workers.
Our data indicate that shift work may be associated with increased risk of death from extrahepatic bile duct cancer in this cohort of Japanese men. The association with gallbladder cancer remains unclear because of the small number of deaths.</description><identifier>ISSN: 1471-2407</identifier><identifier>EISSN: 1471-2407</identifier><identifier>DOI: 10.1186/s12885-015-1722-y</identifier><identifier>PMID: 26490349</identifier><language>eng</language><publisher>England: BioMed Central Ltd</publisher><subject>Adult ; Aged ; Bile ducts ; Biliary Tract Neoplasms - mortality ; Biliary Tract Neoplasms - pathology ; Body mass index ; Cancer ; Care and treatment ; Cholangiocarcinoma ; Circadian rhythm ; Cohort analysis ; Death ; Development and progression ; Diabetes ; Family medical history ; Gallbladder cancer ; Gallstones ; Genetic aspects ; Humans ; Informed consent ; Japan ; Life Style ; Male ; Medical prognosis ; Middle Aged ; Oncology, Experimental ; Pancreatic cancer ; Risk Factors ; Self employment ; Shift work ; Smoking ; Tumors ; Type 2 diabetes ; Work Schedule Tolerance</subject><ispartof>BMC cancer, 2015-10, Vol.15 (1), p.757-757, Article 757</ispartof><rights>COPYRIGHT 2015 BioMed Central Ltd.</rights><rights>Copyright BioMed Central 2015</rights><rights>Lin et al. 2015</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c669t-e506b4fbfd065a024d2517d6b0543784269be8c1d05b9081705c9f29a87ebfc73</citedby><cites>FETCH-LOGICAL-c669t-e506b4fbfd065a024d2517d6b0543784269be8c1d05b9081705c9f29a87ebfc73</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4618019/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4618019/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,315,728,781,785,865,886,27929,27930,53796,53798</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/26490349$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Lin, Yingsong</creatorcontrib><creatorcontrib>Nishiyama, Takeshi</creatorcontrib><creatorcontrib>Kurosawa, Michiko</creatorcontrib><creatorcontrib>Tamakoshi, Akiko</creatorcontrib><creatorcontrib>Kubo, Tatsuhiko</creatorcontrib><creatorcontrib>Fujino, Yoshihisa</creatorcontrib><creatorcontrib>Kikuchi, Shogo</creatorcontrib><creatorcontrib>JACC Study Group</creatorcontrib><creatorcontrib>for the JACC Study Group</creatorcontrib><title>Association between shift work and the risk of death from biliary tract cancer in Japanese men</title><title>BMC cancer</title><addtitle>BMC Cancer</addtitle><description>There is increasing evidence suggesting that shift work involving night work may increase cancer risk.
We examined the association between working rotating shifts and the risk of death from biliary tract cancer among Japanese men who participated in the Japan Collaborative Cohort Study. Of the 46,395 men recruited, 22,224 men aged 40-65 at baseline (1988-1990) who reported working full-time or were self-employed were included in the present analysis. The study subjects were followed through December 31, 2009. Information regarding occupation and lifestyle factors was collected using a self-administered questionnaire. Cox proportional hazard models were used to estimate the hazard ratio (HR) and 95 % confidence interval (CI) for the risk of death from biliary tract cancer in relation to shift work.
During a mean 17-year follow-up, we observed 94 biliary tract cancer deaths, including 23 deaths from gallbladder cancer and 71 deaths from extrahepatic bile duct cancer. Overall, shift work was associated with a statistically non-significant increase in the risk of biliary tract cancer, with an HR of 1.50 (95 % CI: 0.81-2.77), among rotating shift workers. When the analysis was limited to extrahepatic bile duct cancer, a significant association appeared, with a multivariable-adjusted HR of 1.93 (95 % CI: 1.00-3.72) for rotating shift workers.
Our data indicate that shift work may be associated with increased risk of death from extrahepatic bile duct cancer in this cohort of Japanese men. The association with gallbladder cancer remains unclear because of the small number of deaths.</description><subject>Adult</subject><subject>Aged</subject><subject>Bile ducts</subject><subject>Biliary Tract Neoplasms - mortality</subject><subject>Biliary Tract Neoplasms - pathology</subject><subject>Body mass index</subject><subject>Cancer</subject><subject>Care and treatment</subject><subject>Cholangiocarcinoma</subject><subject>Circadian rhythm</subject><subject>Cohort analysis</subject><subject>Death</subject><subject>Development and progression</subject><subject>Diabetes</subject><subject>Family medical history</subject><subject>Gallbladder cancer</subject><subject>Gallstones</subject><subject>Genetic aspects</subject><subject>Humans</subject><subject>Informed consent</subject><subject>Japan</subject><subject>Life Style</subject><subject>Male</subject><subject>Medical prognosis</subject><subject>Middle Aged</subject><subject>Oncology, Experimental</subject><subject>Pancreatic cancer</subject><subject>Risk Factors</subject><subject>Self employment</subject><subject>Shift work</subject><subject>Smoking</subject><subject>Tumors</subject><subject>Type 2 diabetes</subject><subject>Work Schedule Tolerance</subject><issn>1471-2407</issn><issn>1471-2407</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2015</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><recordid>eNptkl1rHCEUhofS0ny0P6A3RSiU9GJSdZ1RbwpL6EdKoNCP24rjHHdMZnSjTtP993XZNOyW4oWiz3k55_WtqhcEnxMi2reJUCGaGpOmJpzSevOoOiaMk5oyzB_vnY-qk5SuMSZcYPG0OqItk3jB5HH1c5lSME5nFzzqIN8BeJQGZzO6C_EGad-jPACKLt2gYFEPOg_IxjChzo1Oxw3KUZuMjPYGInIefdZr7SEBmsA_q55YPSZ4fr-fVj8-vP9-8am--vLx8mJ5VZu2lbmGBrcds53tcdtoTFlPG8L7tsMNW3DBaCs7EIb0uOkkFoTjxkhLpRYcOmv44rR6t9Ndz90EvQFfuhrVOrqptKiCdurwxbtBrcIvxVoiMJFF4OxeIIbbGVJWk0sGxrGMEuakir9cSspbUdBX_6DXYY6-jFcoLgUtPe9RKz2Cct6GrU9bUbVsGGGYUrYo1Pl_qLJ6mJwJHqwr9wcFbw4KCpPhd17pOSV1-e3rIft6jx1Aj3lIYZy3f50OQbIDTQwpRbAPxhGstklTu6SpkrStE1RtSs3LfccfKv5Ga_EHjCPLzw</recordid><startdate>20151021</startdate><enddate>20151021</enddate><creator>Lin, Yingsong</creator><creator>Nishiyama, Takeshi</creator><creator>Kurosawa, Michiko</creator><creator>Tamakoshi, Akiko</creator><creator>Kubo, Tatsuhiko</creator><creator>Fujino, Yoshihisa</creator><creator>Kikuchi, Shogo</creator><general>BioMed Central Ltd</general><general>BioMed Central</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>ISR</scope><scope>3V.</scope><scope>7TO</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>H94</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20151021</creationdate><title>Association between shift work and the risk of death from biliary tract cancer in Japanese men</title><author>Lin, Yingsong ; Nishiyama, Takeshi ; Kurosawa, Michiko ; Tamakoshi, Akiko ; Kubo, Tatsuhiko ; Fujino, Yoshihisa ; Kikuchi, Shogo</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c669t-e506b4fbfd065a024d2517d6b0543784269be8c1d05b9081705c9f29a87ebfc73</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2015</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Bile ducts</topic><topic>Biliary Tract Neoplasms - mortality</topic><topic>Biliary Tract Neoplasms - pathology</topic><topic>Body mass index</topic><topic>Cancer</topic><topic>Care and treatment</topic><topic>Cholangiocarcinoma</topic><topic>Circadian rhythm</topic><topic>Cohort analysis</topic><topic>Death</topic><topic>Development and progression</topic><topic>Diabetes</topic><topic>Family medical history</topic><topic>Gallbladder cancer</topic><topic>Gallstones</topic><topic>Genetic aspects</topic><topic>Humans</topic><topic>Informed consent</topic><topic>Japan</topic><topic>Life Style</topic><topic>Male</topic><topic>Medical prognosis</topic><topic>Middle Aged</topic><topic>Oncology, Experimental</topic><topic>Pancreatic cancer</topic><topic>Risk Factors</topic><topic>Self employment</topic><topic>Shift work</topic><topic>Smoking</topic><topic>Tumors</topic><topic>Type 2 diabetes</topic><topic>Work Schedule Tolerance</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Lin, Yingsong</creatorcontrib><creatorcontrib>Nishiyama, Takeshi</creatorcontrib><creatorcontrib>Kurosawa, Michiko</creatorcontrib><creatorcontrib>Tamakoshi, Akiko</creatorcontrib><creatorcontrib>Kubo, Tatsuhiko</creatorcontrib><creatorcontrib>Fujino, Yoshihisa</creatorcontrib><creatorcontrib>Kikuchi, Shogo</creatorcontrib><creatorcontrib>JACC Study Group</creatorcontrib><creatorcontrib>for the JACC Study Group</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Gale In Context: Science</collection><collection>ProQuest Central (Corporate)</collection><collection>Oncogenes and Growth Factors Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>Proquest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Access via ProQuest (Open Access)</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>BMC cancer</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Lin, Yingsong</au><au>Nishiyama, Takeshi</au><au>Kurosawa, Michiko</au><au>Tamakoshi, Akiko</au><au>Kubo, Tatsuhiko</au><au>Fujino, Yoshihisa</au><au>Kikuchi, Shogo</au><aucorp>JACC Study Group</aucorp><aucorp>for the JACC Study Group</aucorp><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Association between shift work and the risk of death from biliary tract cancer in Japanese men</atitle><jtitle>BMC cancer</jtitle><addtitle>BMC Cancer</addtitle><date>2015-10-21</date><risdate>2015</risdate><volume>15</volume><issue>1</issue><spage>757</spage><epage>757</epage><pages>757-757</pages><artnum>757</artnum><issn>1471-2407</issn><eissn>1471-2407</eissn><abstract>There is increasing evidence suggesting that shift work involving night work may increase cancer risk.
We examined the association between working rotating shifts and the risk of death from biliary tract cancer among Japanese men who participated in the Japan Collaborative Cohort Study. Of the 46,395 men recruited, 22,224 men aged 40-65 at baseline (1988-1990) who reported working full-time or were self-employed were included in the present analysis. The study subjects were followed through December 31, 2009. Information regarding occupation and lifestyle factors was collected using a self-administered questionnaire. Cox proportional hazard models were used to estimate the hazard ratio (HR) and 95 % confidence interval (CI) for the risk of death from biliary tract cancer in relation to shift work.
During a mean 17-year follow-up, we observed 94 biliary tract cancer deaths, including 23 deaths from gallbladder cancer and 71 deaths from extrahepatic bile duct cancer. Overall, shift work was associated with a statistically non-significant increase in the risk of biliary tract cancer, with an HR of 1.50 (95 % CI: 0.81-2.77), among rotating shift workers. When the analysis was limited to extrahepatic bile duct cancer, a significant association appeared, with a multivariable-adjusted HR of 1.93 (95 % CI: 1.00-3.72) for rotating shift workers.
Our data indicate that shift work may be associated with increased risk of death from extrahepatic bile duct cancer in this cohort of Japanese men. The association with gallbladder cancer remains unclear because of the small number of deaths.</abstract><cop>England</cop><pub>BioMed Central Ltd</pub><pmid>26490349</pmid><doi>10.1186/s12885-015-1722-y</doi><tpages>1</tpages><oa>free_for_read</oa></addata></record> |
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| subjects | Adult Aged Bile ducts Biliary Tract Neoplasms - mortality Biliary Tract Neoplasms - pathology Body mass index Cancer Care and treatment Cholangiocarcinoma Circadian rhythm Cohort analysis Death Development and progression Diabetes Family medical history Gallbladder cancer Gallstones Genetic aspects Humans Informed consent Japan Life Style Male Medical prognosis Middle Aged Oncology, Experimental Pancreatic cancer Risk Factors Self employment Shift work Smoking Tumors Type 2 diabetes Work Schedule Tolerance |
| title | Association between shift work and the risk of death from biliary tract cancer in Japanese men |
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