Comparison against 186 canid whole-genome sequences reveals survival strategies of an ancient clonally transmissible canine tumor

Canine transmissible venereal tumor (CTVT) is a parasitic cancer clone that has propagated for thousands of years via sexual transfer of malignant cells. Little is understood about the mechanisms that converted an ancient tumor into the world's oldest known continuously propagating somatic cell...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Genome research 2015-11, Vol.25 (11), p.1646-1655
Hauptverfasser:	Decker, Brennan, Davis, Brian W, Rimbault, Maud, Long, Adrienne H, Karlins, Eric, Jagannathan, Vidhya, Reiman, Rebecca, Parker, Heidi G, Drögemüller, Cord, Corneveaux, Jason J, Chapman, Erica S, Trent, Jeffery M, Leeb, Tosso, Huentelman, Matthew J, Wayne, Robert K, Karyadi, Danielle M, Ostrander, Elaine A
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Apoptosis Autoantigens - genetics CARD Signaling Adaptor Proteins - genetics Cell Adhesion Molecules - genetics Cell Line, Tumor Cell Lineage - genetics Collagen Type XI - genetics DNA-Binding Proteins - genetics Dog Diseases - diagnosis Dog Diseases - genetics Dogs - genetics Genetic Association Studies Genetic Variation Genome Guanine Nucleotide Exchange Factors - genetics Heparan Sulfate Proteoglycans - genetics Microfilament Proteins - genetics Mutation Myotonin-Protein Kinase - genetics Phylogeny Principal Component Analysis Sequence Analysis, DNA Venereal Tumors, Veterinary - diagnosis Venereal Tumors, Veterinary - genetics
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!