Metastatic bladder cancer cells distinctively sense and respond to physical cues of collagen fibril-mimetic nanotopography

Tumor metastasis is characterized by enhanced invasiveness and migration of tumor cells through the extracellular matrix (ECM), resulting in extravasation into the blood and lymph and colonization at secondary sites. The ECM provides a physical scaffold consisting of components such as collagen fibr...

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Veröffentlicht in:Experimental biology and medicine (Maywood, N.J.) N.J.), 2015-05, Vol.240 (5), p.601-610
Hauptverfasser: Iuliano, James N, Kutscha, Paul D, Biderman, NJ, Subbaram, Sita, Groves, Timothy R, Tenenbaum, Scott A, Hempel, Nadine
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Sprache:eng
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