Methylglycol chitosan and a synthetic TLR4 agonist enhance immune responses to influenza vaccine administered sublingually

Abstract Influenza is a vaccine-preventable contagious respiratory illness caused by influenza (flu) viruses which can lead to hospitalization and sometimes even death. Current flu vaccines delivered intramuscularly (IM) or intradermally (ID) are less effective at eliciting protective mucosal immune...

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Veröffentlicht in:Vaccine 2015-10, Vol.33 (43), p.5845-5853
Hauptverfasser: Spinner, Justin L, Oberoi, Hardeep S, Yorgensen, Yvonne M, Poirier, Danielle S, Burkhart, David J, Plante, Martin, Evans, Jay T
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Sprache:eng
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