Degradation of proton depth dose distributions attributable to microstructures in lung‐equivalent material

Purpose: The purpose of the work reported here was to investigate the influence of sub‐millimeter size heterogeneities on the degradation of the distal edges of proton beams and to validate Monte Carlo (MC) methods’ ability to correctly predict such degradation. Methods: A custom‐designed high‐resol...

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Veröffentlicht in:	Medical physics (Lancaster) 2015-11, Vol.42 (11), p.6425-6432
Hauptverfasser:	Titt, Uwe, Sell, Martin, Unkelbach, Jan, Bangert, Mark, Mirkovic, Dragan, Oelfke, Uwe, Mohan, Radhe
Format:	Artikel
Sprache:	eng
Schlagworte:	60 APPLIED LIFE SCIENCES Absorption, Radiation - physiology ANIMAL TISSUES Biological material, e.g. blood, urine Haemocytometers biological tissues Biomimetic Materials - chemistry BRAGG CURVE Computed tomography Computer Simulation Computerised tomographs computerised tomography COMPUTERIZED SIMULATION COMPUTERIZED TOMOGRAPHY convolution DEPTH DOSE DISTRIBUTIONS dose degradation dosimetry Dosimetry/exposure assessment Humans Ion beams lung Lung - physiology lung tissue LUNGS measurements Medical imaging Medical treatment planning MICROSTRUCTURE Models, Biological Modulators Monte Carlo MONTE CARLO METHOD Monte Carlo methods PHANTOMS PROTON BEAMS proton therapy Proton Therapy - methods Protons RADIATION DOSES radiation therapy Radiation Therapy Physics Radiotherapy Dosage Scattering, Radiation Scintigraphy SPATIAL RESOLUTION Therapeutic applications, including brachytherapy Tissues
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