Expression profiling of lymph nodes in tuberculosis patients reveal inflammatory milieu at site of infection

Extrapulmonary manifestations constitute 15 to 20% of tuberculosis cases, with lymph node tuberculosis (LNTB) as the most common form of infection. However, diagnosis and treatment advances are hindered by lack of understanding of LNTB biology. To identify host response, Mycobacterium tuberculosis i...

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Veröffentlicht in:	Scientific reports 2015-10, Vol.5 (1), p.15214-15214, Article 15214
Hauptverfasser:	Maji, Abhijit, Misra, Richa, Kumar Mondal, Anupam, Kumar, Dhirendra, Bajaj, Divya, Singhal, Anshika, Arora, Gunjan, Bhaduri, Asani, Sajid, Andaleeb, Bhatia, Sugandha, Singh, Sompal, Singh, Harshvardhan, Rao, Vivek, Dash, Debasis, Baby Shalini, E, Sarojini Michael, Joy, Chaudhary, Anil, Gokhale, Rajesh S., Singh, Yogendra
Format:	Artikel
Sprache:	eng
Schlagworte:	38/90 45/61 631/337/2019 692/699/255/1856 82/51 82/58 Adolescent Adult Child Cytokines - genetics Cytokines - metabolism Epoxide Hydrolases - genetics Epoxide Hydrolases - metabolism Fatty Acids - metabolism Female Gene Expression Profiling Humanities and Social Sciences Humans Immunohistochemistry Infections Inflammation Lipid Metabolism - genetics Lymph nodes Lymph Nodes - metabolism Lymphatic system Male Matrix Metalloproteinases - genetics Matrix Metalloproteinases - metabolism Metabolism multidisciplinary Proteomics Real-Time Polymerase Chain Reaction Science Th1 Cells - immunology Th1 Cells - metabolism Th2 Cells - immunology Th2 Cells - metabolism Transcriptome Tuberculosis Tuberculosis, Lymph Node - metabolism Tuberculosis, Lymph Node - pathology
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