Short-term Peripheral Auditory Effects of Cranial Irradiation: A Mouse Model

Objectives: Assess postcranial irradiation: (1) short-term threshold shift, (2) short-term peripheral auditory histopathology, and (3) the mouse as an experimental model. Methods: Adult mice were exposed to single-dose radiation of 10 to 60 Gy. Pre- and post-irradiation (baseline, 2-8 days) audiomet...

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Veröffentlicht in:	Annals of otology, rhinology & laryngology rhinology & laryngology, 2015-11, Vol.124 (11), p.903-910
Hauptverfasser:	Gasser Rutledge, Krysta L., Prasad, Kumar G., Emery, Kara R., Mikulec, Anthony A., Varvares, Mark, Gratton, Michael Anne
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Auditory Threshold - radiation effects Cochlea - pathology Cochlea - radiation effects Cranial Irradiation - adverse effects Cranial Irradiation - methods Evoked Potentials, Auditory, Brain Stem - radiation effects Mice Radiation Injuries, Experimental Spiral Ganglion - pathology Spiral Ganglion - radiation effects
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