Bioluminescent, Nonlytic, Real-Time Cell Viability Assay and Use in Inhibitor Screening

Real-time continuous monitoring of cellular processes offers distinct advantages over traditional endpoint assays. A comprehensive representation of the changes occurring in live cells over the entire length of an experiment provides information about the biological status of the cell and informs de...

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Veröffentlicht in:	Assay and drug development technologies 2015-10, Vol.13 (8), p.456-465
Hauptverfasser:	Duellman, Sarah J, Zhou, Wenhui, Meisenheimer, Poncho, Vidugiris, Gediminas, Cali, James J, Gautam, Prson, Wennerberg, Krister, Vidugiriene, Jolanta
Format:	Artikel
Sprache:	eng
Schlagworte:	Antineoplastic Agents - analysis Antineoplastic Agents - pharmacology Apoptosis - drug effects Apoptosis - physiology Cell Survival - drug effects Cell Survival - physiology Computer Systems Dose-Response Relationship, Drug Drug Evaluation, Preclinical - methods Humans K562 Cells Luminescent Measurements - methods Original Small Molecule Libraries - analysis Small Molecule Libraries - pharmacology
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