Frequent down-regulation of ABC transporter genes in prostate cancer

ATP-binding cassette (ABC) transporters are transmembrane proteins responsible for the efflux of a wide variety of substrates, including steroid metabolites, through the cellular membranes. For better characterization of the role of ABC transporters in prostate cancer (PCa) development, the profile...

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Veröffentlicht in:	BMC cancer 2015-10, Vol.15 (1), p.683-683, Article 683
Hauptverfasser:	Demidenko, Rita, Razanauskas, Deividas, Daniunaite, Kristina, Lazutka, Juozas Rimantas, Jankevicius, Feliksas, Jarmalaite, Sonata
Format:	Artikel
Sprache:	eng
Schlagworte:	ABC transporters Analysis Androgens ATP Binding Cassette Transporter, Sub-Family B - genetics ATP-Binding Cassette Transporters - genetics Cancer Cancer therapies Cluster Analysis CpG Islands DNA Methylation Down-Regulation Gene expression Gene Expression Profiling Gene Expression Regulation, Neoplastic Genes Genetic aspects Genetic research Humans Male Membrane proteins Metabolites Methylation Multigene Family Neoplasm Grading Neoplasm Staging Prostate cancer Prostatic Neoplasms - genetics Prostatic Neoplasms - pathology Steroids Thermal cycling Transcription Initiation Site Tumors
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