Induction of Mincle by Helicobacter pylori and consequent anti-inflammatory signaling denote a bacterial survival strategy

Evasion of innate immune recognition is one of the key strategies for persistence of Helicobacter pylori , by virtue of its ability to modulate or escape the host innate immune receptors and signaling pathways. C-type lectin receptors (CLRs) predominantly expressed by macrophages are pivotal in tail...

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Veröffentlicht in:	Scientific reports 2015-10, Vol.5 (1), p.15049-15049, Article 15049
Hauptverfasser:	Devi, Savita, Rajakumara, Eerappa, Ahmed, Niyaz
Format:	Artikel
Sprache:	eng
Schlagworte:	13 13/21 14 14/1 14/63 631/250/255/1918 631/326/88 Amino Acid Sequence Antigens Binding Sites Cell Line Computer applications Cytokines Functional plasticity Gene Expression Regulation Helicobacter pylori Helicobacter pylori - immunology Humanities and Social Sciences Humans Immune clearance Immune Evasion Immune response Immunomodulation Inflammation Innate immunity Interleukin-10 - biosynthesis Interleukin-10 - immunology Lectins, C-Type - antagonists & inhibitors Lectins, C-Type - genetics Lectins, C-Type - immunology Lewis antigens Lipopolysaccharides Lipopolysaccharides - chemistry Lipopolysaccharides - immunology Macrophage Activation Macrophages Macrophages - immunology Macrophages - microbiology Models, Molecular Molecular Sequence Data multidisciplinary Protein Binding Protein Interaction Domains and Motifs Receptors, Immunologic - antagonists & inhibitors Receptors, Immunologic - genetics Receptors, Immunologic - immunology RNA, Small Interfering - genetics RNA, Small Interfering - metabolism Science Sequence Alignment Signal Transduction siRNA T cell receptors Tumor Necrosis Factor-alpha - biosynthesis Tumor Necrosis Factor-alpha - immunology
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