Osmotic Regulation Is Required for Cancer Cell Survival under Solid Stress

For a solid tumor to grow, it must be able to support the compressive stress that is generated as it presses against the surrounding tissue. Although the literature suggests a role for the cytoskeleton in counteracting these stresses, there has been no systematic evaluation of which filaments are re...

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Veröffentlicht in:Biophysical journal 2015-10, Vol.109 (7), p.1334-1337
Hauptverfasser: McGrail, Daniel J., McAndrews, Kathleen M., Brandenburg, Chandler P., Ravikumar, Nithin, Kieu, Quang Minh N., Dawson, Michelle R.
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Sprache:eng
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