miR‐148a dependent apoptosis of bladder cancer cells is mediated in part by the epigenetic modifier DNMT1

Urothelial cell carcinoma of the bladder (UCCB) is the most common form of bladder cancer and it is estimated that ∼15,000 people in the United States succumbed to this disease in 2013. Bladder cancer treatment options are limited and research to understand the molecular mechanisms of this disease i...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Molecular carcinogenesis 2016-05, Vol.55 (5), p.757-767
Hauptverfasser:	Lombard, Alan P., Mooso, Benjamin A., Libertini, Stephen J., Lim, Rebecca M., Nakagawa, Rachel M., Vidallo, Kathleen D., Costanzo, Nicole C., Ghosh, Paramita M., Mudryj, Maria
Format:	Artikel
Sprache:	eng
Schlagworte:	Apoptosis Bladder cancer Cancer cell cycle Cell Line, Tumor Cell Survival Chemotherapy cisplatin Cisplatin - pharmacology DNA (Cytosine-5-)-Methyltransferase 1 DNA (Cytosine-5-)-Methyltransferases - genetics DNA methyltransferase (DNMT1) Down-Regulation doxorubicin Doxorubicin - pharmacology Drug Synergism Epigenesis, Genetic Epigenetics Gene Expression Regulation, Neoplastic Genes Humans MicroRNAs MicroRNAs - genetics miR‐148a Signal transduction Tumor suppressor genes Urinary Bladder Neoplasms - genetics Urinary Bladder Neoplasms - pathology Urothelium - pathology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!