Dental extraction in patients receiving dual antiplatelet therapy
Dual antiplatelet therapy consists of administering antiplatelet (antiaggregant) drugs (clopidogrel and aspirin) to prevent thrombotic processes, as a preventative measure in patients with acute coronary disease, or in patients subjected to percutaneous coronary intervention. The purpose of this stu...
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| Veröffentlicht in: | Medicina oral, patología oral y cirugía bucal patología oral y cirugía bucal, 2015-09, Vol.20 (5), p.e616-e620 |
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| creator | Sánchez-Palomino, Paulino Sánchez-Cobo, Paulino Rodriguez-Archilla, Alberto González-Jaranay, Maximino Moreu, Gerardo Calvo-Guirado, José-Luis Peñarrocha-Diago, Miguel Gómez-Moreno, Gerardo |
| description | Dual antiplatelet therapy consists of administering antiplatelet (antiaggregant) drugs (clopidogrel and aspirin) to prevent thrombotic processes, as a preventative measure in patients with acute coronary disease, or in patients subjected to percutaneous coronary intervention.
The purpose of this study was to evaluate the efficacy of a protocol for performing dental extraction in patients receiving dual antiplatelet therapy.
Thirty-two patients undergoing dental extractions were included in the study. The variables evaluated were: collagen-epinephrine fraction, collagen- adenosine diphosphate fraction, surgical surface, post-surgical measures, and adverse effects. Alveolar sutures and gauzes impregnated with an antifibrinolytic agent (tranexamic acid), which the patient pressed in place for 30 minutes, were applied to all patients as post-surgical measures. Descriptive statistics were calculated and analyzed with Student's t-test to compare pairs of quantitative variables; simple regression analysis was performed using Pearson's correlation coefficient. Statistical significance was set at p |
| doi_str_mv | 10.4317/medoral.20510 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4598932</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1708903697</sourcerecordid><originalsourceid>FETCH-LOGICAL-c453t-59f768e882062b18709fef38456c16c4e5807b1944d317944721d27575d19f473</originalsourceid><addsrcrecordid>eNpVUDlPwzAUthCIlsLIijKypPg-FqSqnFIlFpgtN3FaozQJtlPRf49LS1Wm9_Tep-8C4BrBMSVI3K1s2XpTjzFkCJ6AIeJK5lxRfnq0D8BFCJ8QEoEEPwcDzDFFlNEhmDzYJpo6s9_RmyK6tslck3UmunQPmbeFdWvXLLKyTyjTRNfVJtraxiwurTfd5hKcVaYO9mo_R-Dj6fF9-pLP3p5fp5NZXlBGYs5UJbi0UmLI8RxJAVVlKyIp4wXiBbVMQjFHitIyxUpDYFRiwQQrkaqoICNwv-Pt-nkKXSR_KbfuvFsZv9Gtcfr_p3FLvWjXmjIlFcGJ4HZP4Nuv3oaoVy4Utq5NY9s-aCSgVJBwtdXKd9DCtyF4Wx1kENTb2vW-dv1be8LfHHs7oP96Jj-cp3-b</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1708903697</pqid></control><display><type>article</type><title>Dental extraction in patients receiving dual antiplatelet therapy</title><source>MEDLINE</source><source>PubMed Central</source><source>EZB Electronic Journals Library</source><source>PubMed Central Open Access</source><creator>Sánchez-Palomino, Paulino ; Sánchez-Cobo, Paulino ; Rodriguez-Archilla, Alberto ; González-Jaranay, Maximino ; Moreu, Gerardo ; Calvo-Guirado, José-Luis ; Peñarrocha-Diago, Miguel ; Gómez-Moreno, Gerardo</creator><creatorcontrib>Sánchez-Palomino, Paulino ; Sánchez-Cobo, Paulino ; Rodriguez-Archilla, Alberto ; González-Jaranay, Maximino ; Moreu, Gerardo ; Calvo-Guirado, José-Luis ; Peñarrocha-Diago, Miguel ; Gómez-Moreno, Gerardo</creatorcontrib><description>Dual antiplatelet therapy consists of administering antiplatelet (antiaggregant) drugs (clopidogrel and aspirin) to prevent thrombotic processes, as a preventative measure in patients with acute coronary disease, or in patients subjected to percutaneous coronary intervention.
The purpose of this study was to evaluate the efficacy of a protocol for performing dental extraction in patients receiving dual antiplatelet therapy.
Thirty-two patients undergoing dental extractions were included in the study. The variables evaluated were: collagen-epinephrine fraction, collagen- adenosine diphosphate fraction, surgical surface, post-surgical measures, and adverse effects. Alveolar sutures and gauzes impregnated with an antifibrinolytic agent (tranexamic acid), which the patient pressed in place for 30 minutes, were applied to all patients as post-surgical measures. Descriptive statistics were calculated and analyzed with Student's t-test to compare pairs of quantitative variables; simple regression analysis was performed using Pearson's correlation coefficient. Statistical significance was set at p<0.05.
Collagen/epinephrine fraction was 264.53±55.624 seconds with a range of 135 to 300 seconds, and collagen/ADP fraction was 119.41±44.216 seconds, both values being higher than normal. As a result of the post-surgical measures taken, no patients presented post-operative bleeding, hematoma or infection.
Dental extraction was safe for patients receiving dual anti-platelet therapy when using sutures and gauze impregnated with tranexamic acid, which the patient pressed in place for 30 minutes.</description><identifier>ISSN: 1698-6946</identifier><identifier>ISSN: 1698-4447</identifier><identifier>EISSN: 1698-6946</identifier><identifier>DOI: 10.4317/medoral.20510</identifier><identifier>PMID: 26241454</identifier><language>eng</language><publisher>Spain: Medicina Oral S.L</publisher><subject>Adult ; Aged ; Aged, 80 and over ; Clinical Protocols ; Dentistry ; Female ; Humans ; Male ; Middle Aged ; Perioperative Care - methods ; Platelet Aggregation Inhibitors - therapeutic use ; Postoperative Complications - prevention & control ; Tooth Extraction</subject><ispartof>Medicina oral, patología oral y cirugía bucal, 2015-09, Vol.20 (5), p.e616-e620</ispartof><rights>Copyright: © 2015 Medicina Oral S.L. 2015</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c453t-59f768e882062b18709fef38456c16c4e5807b1944d317944721d27575d19f473</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4598932/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4598932/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,723,776,780,881,27903,27904,53769,53771</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/26241454$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Sánchez-Palomino, Paulino</creatorcontrib><creatorcontrib>Sánchez-Cobo, Paulino</creatorcontrib><creatorcontrib>Rodriguez-Archilla, Alberto</creatorcontrib><creatorcontrib>González-Jaranay, Maximino</creatorcontrib><creatorcontrib>Moreu, Gerardo</creatorcontrib><creatorcontrib>Calvo-Guirado, José-Luis</creatorcontrib><creatorcontrib>Peñarrocha-Diago, Miguel</creatorcontrib><creatorcontrib>Gómez-Moreno, Gerardo</creatorcontrib><title>Dental extraction in patients receiving dual antiplatelet therapy</title><title>Medicina oral, patología oral y cirugía bucal</title><addtitle>Med Oral Patol Oral Cir Bucal</addtitle><description>Dual antiplatelet therapy consists of administering antiplatelet (antiaggregant) drugs (clopidogrel and aspirin) to prevent thrombotic processes, as a preventative measure in patients with acute coronary disease, or in patients subjected to percutaneous coronary intervention.
The purpose of this study was to evaluate the efficacy of a protocol for performing dental extraction in patients receiving dual antiplatelet therapy.
Thirty-two patients undergoing dental extractions were included in the study. The variables evaluated were: collagen-epinephrine fraction, collagen- adenosine diphosphate fraction, surgical surface, post-surgical measures, and adverse effects. Alveolar sutures and gauzes impregnated with an antifibrinolytic agent (tranexamic acid), which the patient pressed in place for 30 minutes, were applied to all patients as post-surgical measures. Descriptive statistics were calculated and analyzed with Student's t-test to compare pairs of quantitative variables; simple regression analysis was performed using Pearson's correlation coefficient. Statistical significance was set at p<0.05.
Collagen/epinephrine fraction was 264.53±55.624 seconds with a range of 135 to 300 seconds, and collagen/ADP fraction was 119.41±44.216 seconds, both values being higher than normal. As a result of the post-surgical measures taken, no patients presented post-operative bleeding, hematoma or infection.
Dental extraction was safe for patients receiving dual anti-platelet therapy when using sutures and gauze impregnated with tranexamic acid, which the patient pressed in place for 30 minutes.</description><subject>Adult</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Clinical Protocols</subject><subject>Dentistry</subject><subject>Female</subject><subject>Humans</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Perioperative Care - methods</subject><subject>Platelet Aggregation Inhibitors - therapeutic use</subject><subject>Postoperative Complications - prevention & control</subject><subject>Tooth Extraction</subject><issn>1698-6946</issn><issn>1698-4447</issn><issn>1698-6946</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2015</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpVUDlPwzAUthCIlsLIijKypPg-FqSqnFIlFpgtN3FaozQJtlPRf49LS1Wm9_Tep-8C4BrBMSVI3K1s2XpTjzFkCJ6AIeJK5lxRfnq0D8BFCJ8QEoEEPwcDzDFFlNEhmDzYJpo6s9_RmyK6tslck3UmunQPmbeFdWvXLLKyTyjTRNfVJtraxiwurTfd5hKcVaYO9mo_R-Dj6fF9-pLP3p5fp5NZXlBGYs5UJbi0UmLI8RxJAVVlKyIp4wXiBbVMQjFHitIyxUpDYFRiwQQrkaqoICNwv-Pt-nkKXSR_KbfuvFsZv9Gtcfr_p3FLvWjXmjIlFcGJ4HZP4Nuv3oaoVy4Utq5NY9s-aCSgVJBwtdXKd9DCtyF4Wx1kENTb2vW-dv1be8LfHHs7oP96Jj-cp3-b</recordid><startdate>20150901</startdate><enddate>20150901</enddate><creator>Sánchez-Palomino, Paulino</creator><creator>Sánchez-Cobo, Paulino</creator><creator>Rodriguez-Archilla, Alberto</creator><creator>González-Jaranay, Maximino</creator><creator>Moreu, Gerardo</creator><creator>Calvo-Guirado, José-Luis</creator><creator>Peñarrocha-Diago, Miguel</creator><creator>Gómez-Moreno, Gerardo</creator><general>Medicina Oral S.L</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20150901</creationdate><title>Dental extraction in patients receiving dual antiplatelet therapy</title><author>Sánchez-Palomino, Paulino ; Sánchez-Cobo, Paulino ; Rodriguez-Archilla, Alberto ; González-Jaranay, Maximino ; Moreu, Gerardo ; Calvo-Guirado, José-Luis ; Peñarrocha-Diago, Miguel ; Gómez-Moreno, Gerardo</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c453t-59f768e882062b18709fef38456c16c4e5807b1944d317944721d27575d19f473</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2015</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Clinical Protocols</topic><topic>Dentistry</topic><topic>Female</topic><topic>Humans</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Perioperative Care - methods</topic><topic>Platelet Aggregation Inhibitors - therapeutic use</topic><topic>Postoperative Complications - prevention & control</topic><topic>Tooth Extraction</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Sánchez-Palomino, Paulino</creatorcontrib><creatorcontrib>Sánchez-Cobo, Paulino</creatorcontrib><creatorcontrib>Rodriguez-Archilla, Alberto</creatorcontrib><creatorcontrib>González-Jaranay, Maximino</creatorcontrib><creatorcontrib>Moreu, Gerardo</creatorcontrib><creatorcontrib>Calvo-Guirado, José-Luis</creatorcontrib><creatorcontrib>Peñarrocha-Diago, Miguel</creatorcontrib><creatorcontrib>Gómez-Moreno, Gerardo</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Medicina oral, patología oral y cirugía bucal</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Sánchez-Palomino, Paulino</au><au>Sánchez-Cobo, Paulino</au><au>Rodriguez-Archilla, Alberto</au><au>González-Jaranay, Maximino</au><au>Moreu, Gerardo</au><au>Calvo-Guirado, José-Luis</au><au>Peñarrocha-Diago, Miguel</au><au>Gómez-Moreno, Gerardo</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Dental extraction in patients receiving dual antiplatelet therapy</atitle><jtitle>Medicina oral, patología oral y cirugía bucal</jtitle><addtitle>Med Oral Patol Oral Cir Bucal</addtitle><date>2015-09-01</date><risdate>2015</risdate><volume>20</volume><issue>5</issue><spage>e616</spage><epage>e620</epage><pages>e616-e620</pages><issn>1698-6946</issn><issn>1698-4447</issn><eissn>1698-6946</eissn><abstract>Dual antiplatelet therapy consists of administering antiplatelet (antiaggregant) drugs (clopidogrel and aspirin) to prevent thrombotic processes, as a preventative measure in patients with acute coronary disease, or in patients subjected to percutaneous coronary intervention.
The purpose of this study was to evaluate the efficacy of a protocol for performing dental extraction in patients receiving dual antiplatelet therapy.
Thirty-two patients undergoing dental extractions were included in the study. The variables evaluated were: collagen-epinephrine fraction, collagen- adenosine diphosphate fraction, surgical surface, post-surgical measures, and adverse effects. Alveolar sutures and gauzes impregnated with an antifibrinolytic agent (tranexamic acid), which the patient pressed in place for 30 minutes, were applied to all patients as post-surgical measures. Descriptive statistics were calculated and analyzed with Student's t-test to compare pairs of quantitative variables; simple regression analysis was performed using Pearson's correlation coefficient. Statistical significance was set at p<0.05.
Collagen/epinephrine fraction was 264.53±55.624 seconds with a range of 135 to 300 seconds, and collagen/ADP fraction was 119.41±44.216 seconds, both values being higher than normal. As a result of the post-surgical measures taken, no patients presented post-operative bleeding, hematoma or infection.
Dental extraction was safe for patients receiving dual anti-platelet therapy when using sutures and gauze impregnated with tranexamic acid, which the patient pressed in place for 30 minutes.</abstract><cop>Spain</cop><pub>Medicina Oral S.L</pub><pmid>26241454</pmid><doi>10.4317/medoral.20510</doi><oa>free_for_read</oa></addata></record> |
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| subjects | Adult Aged Aged, 80 and over Clinical Protocols Dentistry Female Humans Male Middle Aged Perioperative Care - methods Platelet Aggregation Inhibitors - therapeutic use Postoperative Complications - prevention & control Tooth Extraction |
| title | Dental extraction in patients receiving dual antiplatelet therapy |
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