In vitro progesterone modulation on bacterial endotoxin-induced production of IL-1β, TNFα, IL-6, IL-8, IL-10, MIP-1α, and MMP-9 in pre-labor human term placenta

During human pregnancy, infection/inflammation represents an important factor that increases the risk of developing preterm labor. The purpose of this study was to determine if pre-treatment with progesterone has an immunomodulatory effect on human placenta production of endotoxin-induced inflammati...

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Veröffentlicht in:	Reproductive biology and endocrinology 2015-10, Vol.13 (1), p.115-115, Article 115
Hauptverfasser:	Garcia-Ruíz, G, Flores-Espinosa, P, Preciado-Martínez, E, Bermejo-Martínez, L, Espejel-Nuñez, A, Estrada-Gutierrez, G, Maida-Claros, R, Flores-Pliego, A, Zaga-Clavellina, Veronica
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Cesarean Section Chemokine CCL3 - biosynthesis Endotoxins - toxicity Female Humans Inflammation Mediators - antagonists & inhibitors Inflammation Mediators - metabolism Interleukin-10 - biosynthesis Interleukin-1beta - biosynthesis Interleukin-6 - biosynthesis Interleukin-8 - biosynthesis Matrix Metalloproteinase 9 - biosynthesis Organ Culture Techniques Placenta - drug effects Placenta - metabolism Pregnancy Progesterone - pharmacology Progesterone - physiology Tumor Necrosis Factor-alpha - biosynthesis Young Adult
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