Expression and Significance of COX-2 and Ki-67 in Hepatolithiasis with Bile Duct Carcinoma

As an induced enzyme, COX-2 expression is elevated under stimuli from inflammatory mediator or growth factor product. Ki-67, a cell cycle-related proliferative antigen, reflects the tissue proliferative activity. This study analyzed the expressional profile of cyclooxygenase-2 (COX-2) and Ki-67 in h...

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Veröffentlicht in:	Medical science monitor 2015-10, Vol.21, p.2943-2949
Hauptverfasser:	Wang, Ping, He, Yu, Ma, Xiaodong, Sun, Beiwang, Huang, Binyuan, Zhu, Canhua, Liu, Yanmin
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Bile Duct Neoplasms - diagnosis Bile Duct Neoplasms - metabolism Bile Duct Neoplasms - pathology Bile Ducts - metabolism Bile Ducts - pathology Carcinoma - diagnosis Carcinoma - metabolism Carcinoma - pathology Clinical Research Cohort Studies Cyclooxygenase 2 - metabolism Female Gene Expression Profiling Gene Expression Regulation, Enzymologic Gene Expression Regulation, Neoplastic Humans Immunohistochemistry Ki-67 Antigen - metabolism Lithiasis - diagnosis Lithiasis - metabolism Lithiasis - pathology Male Middle Aged Prognosis Regression Analysis Treatment Outcome
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