Analysis of DNA methylation landscape reveals the roles of DNA methylation in the regulation of drug metabolizing enzymes

Drug metabolizing enzymes (DMEs) exhibit dramatic inter- and intra-individual variability in expression and activity. However, the mechanisms determining this variability have not been fully elucidated. The aim of this study was to evaluate the biological significance of DNA methylation in the regul...

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Veröffentlicht in:Clinical epigenetics 2015-09, Vol.7 (1), p.105-105, Article 105
Hauptverfasser: Habano, Wataru, Kawamura, Kohei, Iizuka, Natsuki, Terashima, Jun, Sugai, Tamotsu, Ozawa, Shogo
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Sprache:eng
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