Chromatin interaction analysis reveals changes in small chromosome and telomere clustering between epithelial and breast cancer cells

Higher-order chromatin structure is often perturbed in cancer and other pathological states. Although several genetic and epigenetic differences have been charted between normal and breast cancer tissues, changes in higher-order chromatin organization during tumorigenesis have not been fully explore...

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Veröffentlicht in:	Genome Biology 2015-09, Vol.16 (1), p.214-214, Article 214
Hauptverfasser:	Barutcu, A Rasim, Lajoie, Bryan R, McCord, Rachel P, Tye, Coralee E, Hong, Deli, Messier, Terri L, Browne, Gillian, van Wijnen, Andre J, Lian, Jane B, Stein, Janet L, Dekker, Job, Imbalzano, Anthony N, Stein, Gary S
Format:	Artikel
Sprache:	eng
Schlagworte:	Bioinformatics Breast cancer breast neoplasms Breast Neoplasms - genetics Breast Neoplasms - pathology Cancer Cancer cells Carcinogenesis Chromatin Chromatin - genetics Chromosomes Comparative analysis Development and progression Discovery tools Epigenesis, Genetic Epigenetic inheritance epigenetics Epithelial cells Epithelial Cells - metabolism Epithelial Cells - pathology epithelium Female Gene expression Gene Expression Regulation, Neoplastic Genes Genetic aspects Genetic research genome Genomes Genomics Humans Mammary Glands, Human - metabolism Mammary Glands, Human - pathology MCF-7 Cells Morphology neoplasm cells Patient outcomes Stem cells Telomere - genetics Telomeres Tumor cell lines Tumorigenesis Wnt protein
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